Community Research and Development Information Service - CORDIS

New developments in the field of animal testing

The early-stage testing phase of any new drug, prior to its introduction to clinical development stage, involves a series of evaluations in suitable animal models of human disease. Accurate representation of the human pathology within these animal models is crucial if the derived observations regarding drug effect are to have any value.
New developments in the field of animal testing
A research group in Spain has succeeded in developing accurate recording systems for the study of learning and memory processes in mice. This could be a critical development given the difficulties facing pharmaceutical companies in the testing of drugs in animals for neurodegenerative diseases such as Alzheimer's disease.

With the ability to record changes in memory and learning in animals within an experimental setting, these models could be of great assistance in the field of drug testing. For instance in the areas of neurodegenerative diseases. The researchers can provide specially conditioned mice in order to aid pharmacological testing through behavioural, learning and memory studies.

The innovative recording systems allow the study of neuronal processes within the cerebral cortex in key phases of development, such as motor learning. As such they provide ideal basis for animal models of a number of diseases, potentially used for testing the long-term effects of specific drugs on neuronal function.

Pharmaceutical companies active in the field of neurodegenerative diseases are invited to provide support and technical assistance in further developing this application.
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