Community Research and Development Information Service - CORDIS

Developing new diagnostics for oral diseases

Early detection of pathologies is often the key to a positive prognosis. Developing technologies enabling diagnosis at earlier stages of any disease is the goal of researchers worldwide.
Developing new diagnostics for oral diseases
Israeli researchers have developed a technology allowing the objective examination of colour changes of oral lesions and teeth, thus spotting early signs of malignancy and inflammation and even tooth decay. Current evaluations of teeth colour changes and oral lesions is a heavily subjective process, relying on a variety of parameters.

These parameters include the practitioner's observation and experience as well as the lighting of the room, which also changes during the day. These altering parameters make it extremely difficult for comparisons to be made across time and thus accurately detect slight changes in colouration.

As of today, there is no single way to quantify colour changes and thus evaluate these changes over time. The innovative technology, developed in Israel, allows images to be compared without being affected by changes in the ambient light. The software tool quantifies the colour in the lesion and compares it to normal tissue colouration in order to determine whether it is indicative of specific pathologies.

The images can be stored and analysed using a laptop facilitating the application of this technology for a variety of clinical settings. The developers would like to explore collaborative avenues with private companies active in the development of oral diagnostic technologies and bring the product to the market.
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