Community Research and Development Information Service - CORDIS

A simple, green method for including organic compounds in nanoparticles

A Spanish spin-off company has developed a new method for the preparation of solid lipid nanoparticles of organic compounds that can be used by pharmaceutical and cosmetics industries.
A simple, green method for including organic compounds in nanoparticles
Lipid or polymeric nanoparticles are extensively used in many drug and cosmetic applications. One of the key requisites for maintaining their effective activity is to ensure that increased stability is provided to these compounds within their biological environment. Therefore, the active compounds are protected in nanospheres, which enhances the control of the drug release and increases their solubility without affecting their beneficial properties.

The Spanish company has developed an easy, versatile and inexpensive method for the inclusion of various kinds of active organic compounds in nanoparticles. The method is eco-friendly without any requirements on toxic solvents use and thus, improves occupational safety and health. The method uses lipids or polymers that have already been tested in biological formulations and can be run in bulky quantities with minimum waste.

The technique is that offers a high inclusion percentage of the active compound inside the nanoparticle and the derived nanoparticles display increased stability. The spin-off is seeking for industrial partners, who are interested in including this method to their productive process or adapting and optimising formulations for specialised applications. The method is offered for technical co-operation, however other types of collaboration can also be explored.
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