Community Research and Development Information Service - CORDIS



Project ID: 503039
Country: Germany

Quality control for Europe’s brain and tissue banks

Blood banks, sperm banks and even banks that manage stem cells from a baby’s umbilical cord have become quite common in recent years. EU-funded researchers made excellent progress in developing standards for another equally important type of bank – brain banks used for clinical and basic neuroscience research.
Quality control for Europe’s brain and tissue banks
Brain and tissue banks house brains for anatomical research purposes and are of key importance to our understanding of central nervous system (CNS) disorders.

The ‘Network of European Brain and Tissue Banks for Clinical and Basic Neuroscience’ (Brainnet Europe II) project was designed to enhance the quality and standardisation of procedures related to analysis of brain tissue and diagnosis of related diseases.

Specifically, the consortium sought to establish a quality control mechanism for research projects, to standardise diagnoses of neuropathology as related to neurology and psychiatry, to simultaneously raise awareness of standardisation procedures and to develop ‘gold standards’ of excellence in collecting and analysing high quality human post mortem brain tissue including ethical considerations.

Furthermore, the Brainnet Europe II project included training of neuroscientists as well as enhanced data exchange within the network and information dissemination to the public. The consortium organised numerous meetings and workshops, covering areas including tissue analysis, database construction, legal and ethical issues and brain donor recruitment.

The Brainnet Europe II project made a significant contribution to clinical and basic neuroscience by developing methodologies that ensure the highest quality and uniformity of post mortem brain tissue collection, evaluation and diagnosis of disease The outcomes should increase the reliability and applicability of reported data and thus enable better treatments and cures of neuropathological conditions in the near future.

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