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Clinical and pre-clinical evaluation of fosmidomycin and its derivates as antimalarial drugs
ID: ICA4-CT-2001-10078
Start date: 2002-01-01, End date: 2004-12-31
The present project will help to develop fosmidomycin, an inhibitor of the DOXP reductoisomerase, into an antimalarial drug. In parallel to the clinical evaluation of fosmidomycin in human volunteers, tests with derivatives of fosmidomycin with demonstrably improved pharmacolo...
Programme: FP5-INCO 2
Record Number: 60224
Last updated on: 2005-04-12
ID: FI2W0071
Start date: 1991-01-01, End date: 1995-06-30
The Uranium ore body in Oklo is a unique subject in the world, as natural fission reactions occurred there two billion years ago. It provides opportunities for the study of natural analogy with deep radioactive waste disposal, specially radionuclide mass transfer processes to ...
Programme: FP2-RADWASTOM 4C
Record Number: 3787
Last updated on: 1996-01-09
ID: IC18970246
Start date: 1997-10-01, End date: 1999-03-31
* To provide a surveillance system for newly emerging and naturally occurring recombinant HIV-1 strains in Cameroon and Gabon. * To classify sera from HIV infected individuals according to their capacity to neutralise primary isolates representing different genetic clades. * T...
Programme: FP4-INCO
Record Number: 38175
Last updated on: 2001-12-07
ID: IC18970242
Start date: 1997-09-01, End date: 2000-11-30
* Construct mathematical models of the immunological and clinical epidemiology of Plasmodium falciparum (P.f.) malaria, and test the model predictions against observations collected independently of this project. * Use the models for helping to: a) calculate the expected impa...
Programme: FP4-INCO
Record Number: 40184
Last updated on: 2002-04-22
ID: IC18950026
Start date: 1996-01-01, End date: 1997-06-30
* To determine the mechanisms of protection induced by irradiated infective larvae of Loa loa in monkey and of Litomosoides sigmodontis in laboratory mice. * To identify the mechanisms of natural protection against microfilariae of L. sigmodontis in laboratory mice and cotton...
Programme: FP4-INCO
Record Number: 31190
Last updated on: 2001-12-07
ID: IC18960110
Start date: 1996-11-01, End date: 1998-04-30
* To provide a surveillance system for newly emerging and naturally occurring recombinant HIV-1 strains in Cameroon and Gabon. * To classify sera from HIV infected individuals according to their capacity to neutralize primary isolates representing different genetic clades. * T...
Programme: FP4-INCO
Record Number: 34232
Last updated on: 2001-12-07
ID: TS2*0239
Start date: 1989-10-01, End date: 1994-09-30
Programme: FP2-STD 2
Record Number: 2849
Last updated on: 1990-10-02
ID: TS1*0038
Start date: 1984-01-01, End date: 1987-12-31
Programme: PRE-STD 1
Record Number: 2903
Last updated on: 1990-10-02
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List retrieved on: 2018-04-22
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