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Horizon 2020 project information and now also report summaries are available on CORDIS. All H2020 projects can be downloaded from the EU Open Data Portal .

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Factor XII and the contact system: 
cross-talk between thrombosis and inflammation
ID: 311575
Start date: 2013-08-01, End date: 2018-07-31
Combinations of proinflammatory and procoagulant reactions are the unifying principle for a variety of disorders affecting the cardiovascular system. Factor XII (FXII, Hageman factor) is a plasma protease that initiates the contact system. This system starts a cascade of proc...
Programme: FP7-IDEAS-ERC
Record Number: 109422
Last updated on: 2018-01-22
Towards a mechanistic understanding of mRNA localization
ID: 310957
Start date: 2013-01-01, End date: 2018-12-31
The localization of mRNAs has been increasingly recognized as a prominent mode of regulation of gene expression in eukaryotes. Localized RNAs can have crucial roles during animal development, in the maintenance of cell polarity and in nervous system function. Studies of RNA l...
Programme: FP7-IDEAS-ERC
Record Number: 105717
Last updated on: 2017-12-04
Regulation of Chromatin by Combinatorial DNA and Histone Modifications
ID: 309952
Start date: 2013-05-01, End date: 2019-04-30
The normal expression of genes is tightly regulated. Modifications on histones or on DNA play a central role in the control of gene expression and errors in their regulation often result in diseases such as cancer. These modifications can recruit proteins that regulate chroma...
Programme: FP7-IDEAS-ERC
Record Number: 107360
Last updated on: 2017-11-20
Impact of virus infection on the host proteome
ID: 311339
Start date: 2012-11-01, End date: 2017-10-31
Pathogens exploit cellular resources for their own benefit and their propagation. Co-evolution of viruses and their hosts led to the establishment of very specific interactions between both partners. The balance between both, the viral attack and the cellular defense mechanis...
Programme: FP7-IDEAS-ERC
Record Number: 105790
Last updated on: 2017-11-20
NutrImmune: Nutrient-controlled molecular pathways instructing development and function of mucosa-associated innate lymphocytes
ID: 311377
Start date: 2013-03-01, End date: 2018-02-28
The last decade has witnessed an explosion of research into the molecular networks ensuring maintenance of a mutualistic relationship between microbes and host cell networks at mucosal surfaces. Failure of such homeostatic or adaptive programs lead to susceptibility to intest...
Programme: FP7-IDEAS-ERC
Record Number: 107185
Last updated on: 2017-09-03
Dissection of centromeric chromatin and components: A biosynthetic approach
ID: 311674
Start date: 2013-02-01, End date: 2019-01-31
The centromere is one of the most important chromosomal elements. It is required for proper chromosome segregation in mitosis and meiosis and readily recognizable as the primary constriction of mitotic chromosomes. Proper centromere function is essential to ensure genome stab...
Programme: FP7-IDEAS-ERC
Record Number: 106164
Last updated on: 2017-08-22
Bacterial effector secretion: Function and Architecture of the Type 3 Secretion System
ID: 311374
Start date: 2013-01-01, End date: 2017-12-31
Bacterial pathogens secrete effector proteins to manipulate host cells during infection. In Gram-negative bacteria the conserved type 3 secretion system (T3SS) delivers effector proteins to the host cell in a spatiotemporal manner. Although major T3SS constituting components ...
Programme: FP7-IDEAS-ERC
Record Number: 105833
Last updated on: 2017-08-13
Fine Tuning the Final Common Pathway: Molecular Determinants of Motor Unit Development and Plasticity
ID: 311710
Start date: 2012-11-01, End date: 2017-10-31
Motor neurons (MNs) constitute the final common pathway in the generation of behaviors by linking the CNS with the movement apparatus. Herein, MNs diversify into fast, intermediate and slow types whose properties are tuned to the speed, force and endurance of the muscle fiber...
Programme: FP7-IDEAS-ERC
Record Number: 105218
Last updated on: 2017-06-26
Reverse engineering the vertebrate molecular machinery for magnetic biomineralisation
ID: 311552
Start date: 2013-01-01, End date: 2017-12-31
In order to understand distributed biological networks and invent effective molecular therapies, we need to be able to image and control molecular processes across entire live organisms. Although an arsenal of genetically encoded fluorescent sensors and light-activated protei...
Programme: FP7-IDEAS-ERC
Record Number: 106439
Last updated on: 2017-06-12
Mechanistic dissection of myofibrillogenesis and sarcomerogenesis in insect muscle
ID: 310939
Start date: 2013-02-01, End date: 2019-01-31
Higher animals employ a complex muscle network for their daily movements. Proper execution of movements requires individual muscles to form at the correct positions, connect to proper tendons and produce sufficient force. Muscle development is a multi-step process: myoblasts ...
Programme: FP7-IDEAS-ERC
Record Number: 105666
Last updated on: 2017-05-08
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List retrieved on: 2018-08-19
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