Community Research and Development Information Service - CORDIS

Horizon 2020 project information and now also report summaries are available on CORDIS. All H2020 projects can be downloaded from the EU Open Data Portal .

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Molecular Mechanisms of GABAergic synapse formation: spatial segregation in cortical inhibitory inputs
ID: 310021
Start date: 2013-01-01, End date: 2018-06-30
Neuronal circuitries underlying the function of the mammalian cerebral cortex collectively constitute one of the most complex biological systems. As such, unraveling the mechanisms that control their development represents one of the most challenging questions in Science. Und...
Programme: FP7-IDEAS-ERC
Record Number: 105616
Last updated on: 2017-09-24
Understanding the development and function of cerebral cortex folding
ID: 309633
Start date: 2013-01-01, End date: 2018-06-30
The mammalian cerebral cortex was subject to a dramatic expansion in surface area during evolution. This process is recapitulated during development and is accompanied by folding of the cortical sheet, which allows fitting a large cortical surface within a limited cranial vol...
Programme: FP7-IDEAS-ERC
Record Number: 105577
Last updated on: 2017-08-27
Biogenesis of lipid droplets and lipid homeostasis
ID: 309477
Start date: 2013-02-01, End date: 2018-01-31
Organisms and cells face a myriad of environmental changes with periods of nutrient surplus and shortage. It is therefore not surprising that in all kingdoms of life, cells have evolved the means to store energy and thereby minimize the effects of environmental fluctuations. ...
Programme: FP7-IDEAS-ERC
Record Number: 105402
Last updated on: 2016-12-19
Elucidating early pathogenic mechanisms of neurodegeneration in Parkinson's disease through a humanized dynamic in vitro model
ID: 311736
Start date: 2013-07-01, End date: 2018-06-30
Our understanding of Parkinson’s disease (PD) pathogenesis is currently limited by difficulties in obtaining live neurons from patients and the inability to model the sporadic, most frequent, form of PD. It may be possible to overcome these challenges by reprogramming somatic...
Programme: FP7-IDEAS-ERC
Record Number: 108993
Last updated on: 2016-11-28
Epigenetic control and impact of mammalian retrotransposons in pluripotent genomes
ID: 309433
Start date: 2013-07-01, End date: 2018-06-30
Almost half of the human genome is made of Transposable Elements (TEs), whose ongoing activity continually impacts our genome. However, little is known about how the host regulates TEs and their genomic and epigenomic impacts. EpiPluriRetro will advance research in a new grou...
Programme: FP7-IDEAS-ERC
Record Number: 110327
Last updated on: 2016-04-26
Evolutionary genomics of long, non-coding RNAs
ID: 310325
Start date: 2013-01-01, End date: 2017-12-31
Recent genomics analyses have facilitated the discovery of a novel major class of stable transcripts, now called long non-coding RNAs (lncRNAs). A growing number of analyses have implicated lncRNAs in the regulation of gene expression, dosage compensation and imprinting, and ...
Programme: FP7-IDEAS-ERC
Record Number: 105055
Last updated on: 2016-01-08
Lab-in-a-tube and Nanorobotic biosensors
ID: 311529
Start date: 2013-01-01, End date: 2017-12-31
The goal of this project is to develop new types of biosensors based on two different approaches: (i) a new bioanalytic microsystem platform for cell growth, manipulation and analysis using on-chip integrated microtubes and (ii) the use of synthetic self-propelled nanomotors ...
Programme: FP7-IDEAS-ERC
Record Number: 105373
Last updated on: 2016-01-08
The Role of Non-coding RNA in Protein Networks and Neurodegenerative Diseases
ID: 309545
Start date: 2013-01-01, End date: 2017-12-31
"A major portion of the eukaryotic genome is occupied by DNA sequences whose transcripts do not code for proteins. This part of the genome is transcribed in a developmentally regulated manner and in response to external stimuli to produce large numbers of long non-coding RNAs...
Programme: FP7-IDEAS-ERC
Record Number: 105054
Last updated on: 2015-07-22
Spatiotemporal regulation of epidermal stem cells by circadian rhythms: impact on homeostasis and aging
ID: 309502
Start date: 2013-01-01, End date: 2017-12-31
"Most adult stem cells are compartmentalized in functionally deterministic niches where they self-renew and maintain homeostasis. From there, stem cells are instructed by combinations of signals and spatial tensile forces which they translate into a specific behavior. However...
Programme: FP7-IDEAS-ERC
Record Number: 105947
Last updated on: 2015-03-11
Signals for accommodative responses in humans
ID: 309416
Start date: 2012-11-01, End date: 2017-10-31
"Long-term objectives are to identify optical signals that control accommodation and emmetropization of the eye, and to identify the mechanisms that mediate the optical signals. A primary goal is to determine whether accommodation responds to the wavefront characteristics of ...
Programme: FP7-IDEAS-ERC
Record Number: 105744
Last updated on: 2015-03-11
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List retrieved on: 2018-08-22
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