Community Research and Development Information Service - CORDIS

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Factor XII and the contact system: 
cross-talk between thrombosis and inflammation
ID: 311575
Start date: 2013-08-01, End date: 2018-07-31
Combinations of proinflammatory and procoagulant reactions are the unifying principle for a variety of disorders affecting the cardiovascular system. Factor XII (FXII, Hageman factor) is a plasma protease that initiates the contact system. This system starts a cascade of proc...
Programme: FP7-IDEAS-ERC
Record Number: 109422
Last updated on: 2018-01-22
Next generation sequencing for detection of human primary immunodeficiency syndromes characterized by impaired cytotoxic lymphocyte function
ID: 311335
Start date: 2013-05-01, End date: 2018-04-30
Human primary immunodeficiencies affecting cytotoxic lymphocyte function are associated with high morbidity and mortality. They often present as hyperinflammatory syndromes triggered by viral infections, hematological malignancies, or systemic autoimmunity. Although recent ad...
Programme: FP7-IDEAS-ERC
Record Number: 108234
Last updated on: 2018-01-22
An astronomical perspective on Earth's geological record and evolution of life
ID: 291300
Start date: 2012-04-01, End date: 2017-03-31
"This project will develop the use of relict, extraterrestrial minerals in Archean to Cenozoic slowly formed sediments as tracers of events in the solar system and cosmos, and to decipher the possible relation between such events and evolution of life and environmental change...
Programme: FP7-IDEAS-ERC
Record Number: 103157
Last updated on: 2018-01-22
Million-core Molecular Simulation
[PROJECT] MEGASIM - Million-core Molecular Simulation
ID: 258980
Start date: 2011-05-01, End date: 2017-04-30
Molecular simulation has become a standard tool for studying the function of biomolecules, such as proteins, nucleic acids and lipids. Due to increasing computer power and decreasing length scales in engineering, molecular simulation is also increasingly used in microfluidics...
Programme: FP7-IDEAS-ERC
Record Number: 98778
Last updated on: 2018-01-22
The role of parvalbumin interneurons in cognition and behavior
ID: 337069
Start date: 2014-02-01, End date: 2019-01-31
Cognition is a collective term for complex but sophisticated mental processes such as attention, learning, social interaction, language production, decision making and other executive functions. For normal brain function, these higher-order functions need to be aptly regulate...
Programme: FP7-IDEAS-ERC
Record Number: 191310
Last updated on: 2018-01-15
Dissecting genotype-phenotype relationships using high-throughput genomics and carefully selected study populations
ID: 294601
Start date: 2012-05-01, End date: 2017-04-30
A major aim in genome research is to reveal how genetic variation affects phenotypic variation. Here I propose to use high-throughput genomics (whole genome sequencing, transcriptome and epigenome analysis) to screen carefully selected study populations where the chances are ...
Programme: FP7-IDEAS-ERC
Record Number: 103577
Last updated on: 2018-01-03
Analytical Sociology: Theoretical Developments and Empirical Research
ID: 324233
Start date: 2013-03-01, End date: 2018-02-28
This proposal outlines a highly ambitious and path-breaking research program. Through a tightly integrated package of basic theoretical work, strategic empirical research projects, international workshops, and a large number of publications in leading journals, the research p...
Programme: FP7-IDEAS-ERC
Record Number: 107072
Last updated on: 2017-12-07
Genetics and epigenetics of animal welfare
ID: 322206
Start date: 2013-03-01, End date: 2018-02-28
Animal welfare is a topic of highest societal and scientific priority. Here, I propose to use genomic and epigenetic tools to provide a new perspective on the biology of animal welfare. This will reveal mechanisms involved in modulating stress responses. Groundbreaking aspect...
Programme: FP7-IDEAS-ERC
Record Number: 107325
Last updated on: 2017-12-07
Nitride-based nanostructured novel thermoelectric thin-film materials
ID: 335383
Start date: 2013-10-01, End date: 2018-09-30
My recent discovery of the anomalously high thermoelectric power factor of ScN thin films demonstrates that unexpected thermoelectric materials can be found among the early transition-metal and rare-earth nitrides. Corroborated by first-principles calculations, we have well-f...
Programme: FP7-IDEAS-ERC
Record Number: 109138
Last updated on: 2017-12-04
Improved Diagnosis and Management of Heart Disease by 4D Blood Flow Assessment
ID: 310612
Start date: 2013-01-01, End date: 2017-12-31
The primary purpose of the cardiovascular system is to drive, control and maintain blood flow to all parts of the body. Despite the primacy of flow, cardiac diagnostics still rely almost exclusively on tools focused on morphological assessment. The objective of the HEART4FLOW...
Programme: FP7-IDEAS-ERC
Record Number: 106001
Last updated on: 2017-12-04
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List retrieved on: 2018-08-21
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