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Expression and Methylation Status of Genes Regulating Placental Angiogenesis in Normal, Cloned, IVF and Monoparental Sheep Foetuses
ID: 210103
Start date: 2008-10-01, End date: 2012-06-30
Normal placental angiogenesis is critical for embryonic survival and development. Epigenetic modifications, such as methylation of CpG islands, regulate the expression and imprinting of genes. Epigenetic abnormalities have been observed in embryos from assisted reproductive t...
Programme: FP7-IDEAS-ERC
Record Number: 88252
Last updated on: 2017-05-30
Renal stem cells: possible role in kidney pathologies and as new theraputic tools
ID: 205027
Start date: 2008-10-01, End date: 2012-09-30
Chronic Kidney Disease (CKD) affects 11% of the adult population and is considered by the WHO as one of the health emergencies of the 21st century. Although cell therapy might be beneficial for CKD, human stem cells that might be used to improve kidney function were so far un...
Programme: FP7-IDEAS-ERC
Record Number: 87586
Last updated on: 2017-05-30
Hamiltonian Partial Differential Equations: new connections between dynamical systems and PDEs with small divisors phenomena
ID: 204979
Start date: 2008-07-01, End date: 2012-06-30
"The aim of this project of 4 years is to create a research group on Hamiltonian Partial Differential Equations (PDEs) after my new arrival in the University Federico II of Naples as Associate Professor in november 2005. I plan to hire 2 post doc fellows and also to organize ...
Programme: FP7-IDEAS-ERC
Record Number: 87458
Last updated on: 2017-05-30
Aberrant gene expression and muscular dystrophy: role of non-coding RNAs and alternative splicing in the pathogenesis and potential therapies
ID: 204279
Start date: 2008-09-01, End date: 2014-08-31
Our goal is to characterize the molecular pathogenesis of facioscapulohumeral muscular dystrophy (FSHD) in order to develop possible therapeutic approaches. FSHD is the third most important myopathy. Currently, no therapeutic treatment is available for FSHD. Unlike the majori...
Programme: FP7-IDEAS-ERC
Record Number: 87743
Last updated on: 2017-05-30
Leptin, metabolic state and natural regulatory T cells: cellular and molecular basis for a novel immune intervention in autoimmunity
ID: 202579
Start date: 2008-07-01, End date: 2011-10-31
Our Group has been investigating the cellular and molecular mechanisms involving leptin, the adipocyte-derived hormone, in the pathogenesis of autoimmunity such as experimental autoimmune encephalomyelitis (EAE) and multiple sclerosis (MS).We analyzed the serum and cerebro-sp...
Programme: FP7-IDEAS-ERC
Record Number: 87389
Last updated on: 2017-05-30
Self-Modulating Neurons in the Cerebral Cortex: From Molecular Mechanisms to Cortical Network Activities
ID: 200808
Start date: 2008-10-01, End date: 2014-03-31
In the mammalian brain, the neocortex is the site where sensory information is integrated into complex cognitive functions. This is accomplished by the activity of both principal glutamatergic neurons and locally-projecting inhibitory GABAergic interneurons, interconnected in...
Programme: FP7-IDEAS-ERC
Record Number: 88233
Last updated on: 2017-05-30
Mathematics for Shape Memory Technologies in Biomechanics
ID: 200497
Start date: 2008-09-01, End date: 2013-08-31
Shape Memory Alloys (SMAs) are nowadays widely exploited for the realization of innovative devices and have a great impact on the development of a variety of biomedical applications ranging from orthodontic archwires to vascular stents. The design, realization, and optimizati...
Programme: FP7-IDEAS-ERC
Record Number: 87932
Last updated on: 2017-05-30
Generative Models of Human Cognition
ID: 210922
Start date: 2008-06-01, End date: 2013-05-31
A fundamental issue in the study of human cognition is what computations are carried out by the brain to implement cognitive processes. The connectionist framework assumes that cognitive processes are implemented in terms of complex, nonlinear interactions among a large numbe...
Programme: FP7-IDEAS-ERC
Record Number: 87425
Last updated on: 2017-05-29
Social Insurance and Welfare-to-Work Programs: Optimal Design and Structural Evaluation
ID: 210908
Start date: 2008-07-01, End date: 2011-06-30
This project has three main goals. First, to improve the theoretical understanding of the design of optimal social insurance and Welfare-to-Work (WTW) programs. Second, to provide a new structural framework for the evaluation of existing policies. The framework is integrated ...
Programme: FP7-IDEAS-ERC
Record Number: 87424
Last updated on: 2017-05-29
Uncovering the Secrets of an Earthquake: Multidisciplinary Study of Physico-Chemical Processes During the Seismic Cycle
ID: 205175
Start date: 2008-06-01, End date: 2013-05-31
Southern Europe and Turkey lie within the highest seismic risk areas in the world. Understanding the physico-chemical processes controlling earthquake generation is essential in seismic hazard assessment. Destructive earthquakes nucleate at depth (10-15 km), therefore monitor...
Programme: FP7-IDEAS-ERC
Record Number: 87461
Last updated on: 2017-05-29
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List retrieved on: 2018-02-19
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