Community Research and Development Information Service - CORDIS

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Adipocyte Differentiation and Metabolic Functions in Obesity and Type 2 Diabetes
ID: 205641
Start date: 2008-07-01, End date: 2013-06-30
Obesity associated disorders such as T2D, hypertension and CVD, commonly referred to as the “metabolic syndrome”, are prevalent diseases of industrialized societies. Deranged adipose tissue proliferation and differentiation contribute significantly to the development of these...
Programme: FP7-IDEAS-ERC
Record Number: 87463
Last updated on: 2017-05-30
Molecularly targeted therapy for T cell acute lymphoblastic leukemia
ID: 205252
Start date: 2008-10-01, End date: 2013-09-30
T cell acute lymphoblastic leukemia (T-ALL) is an aggressive T cell malignancy that is most common in children and adolescents. Our current understanding of the molecular genetics of T-ALL indicates that leukemic transformation of thymocytes is caused by the cooperation of mu...
Programme: FP7-IDEAS-ERC
Record Number: 88247
Last updated on: 2017-05-30
Olfactory perception in Drosophila: analysis of a novel iGluR-related family of odorant receptors
ID: 205202
Start date: 2008-07-01, End date: 2013-06-30
Chemosensory systems permit organisms to perceive diverse chemicals in the environment signalling the presence of food, dangers, kin or mates. How a specific chemical stimulus is recognised and converted into neural activity that provokes the appropriate behaviour is a fundam...
Programme: FP7-IDEAS-ERC
Record Number: 87410
Last updated on: 2017-05-30
Renal stem cells: possible role in kidney pathologies and as new theraputic tools
ID: 205027
Start date: 2008-10-01, End date: 2012-09-30
Chronic Kidney Disease (CKD) affects 11% of the adult population and is considered by the WHO as one of the health emergencies of the 21st century. Although cell therapy might be beneficial for CKD, human stem cells that might be used to improve kidney function were so far un...
Programme: FP7-IDEAS-ERC
Record Number: 87586
Last updated on: 2017-05-30
Hamiltonian Partial Differential Equations: new connections between dynamical systems and PDEs with small divisors phenomena
ID: 204979
Start date: 2008-07-01, End date: 2012-06-30
"The aim of this project of 4 years is to create a research group on Hamiltonian Partial Differential Equations (PDEs) after my new arrival in the University Federico II of Naples as Associate Professor in november 2005. I plan to hire 2 post doc fellows and also to organize ...
Programme: FP7-IDEAS-ERC
Record Number: 87458
Last updated on: 2017-05-30
The geometry of topological quantum field theories
ID: 204757
Start date: 2009-01-01, End date: 2014-06-30
The predictive power of quantum field theory (QFT) is a perpetual driving force in geometry. Examples include the invention of Frobenius manifolds, mixed twistor structures, primitive forms, and harmonic bundles, up to the discovery of the McKay correspondence, mirror symmetr...
Programme: FP7-IDEAS-ERC
Record Number: 87585
Last updated on: 2017-05-30
Aberrant gene expression and muscular dystrophy: role of non-coding RNAs and alternative splicing in the pathogenesis and potential therapies
ID: 204279
Start date: 2008-09-01, End date: 2014-08-31
Our goal is to characterize the molecular pathogenesis of facioscapulohumeral muscular dystrophy (FSHD) in order to develop possible therapeutic approaches. FSHD is the third most important myopathy. Currently, no therapeutic treatment is available for FSHD. Unlike the majori...
Programme: FP7-IDEAS-ERC
Record Number: 87743
Last updated on: 2017-05-30
Epigenetic determinants of the genome that govern cellular plasticity
ID: 204264
Start date: 2008-10-01, End date: 2013-09-30
Differentiation events in mammalian development involve stable resetting of transcriptional programs, which entails changes in the epigenetic state of target sequences defined by modifications of DNA and bound nucleosomes. These recently identified epigenetic layers modulate ...
Programme: FP7-IDEAS-ERC
Record Number: 87453
Last updated on: 2017-05-30
Towards symplectic Teichmueller theory
ID: 205349
Start date: 2008-07-01, End date: 2013-06-30
"Over the last decade, homological algebra has entered symplectic topology, largely thanks to the appearance of Fukaya categories in homological mirror symmetry. Applications of these new methods and ideas are still scarce. We propose a fundamentally new approach to studying ...
Programme: FP7-IDEAS-ERC
Record Number: 87462
Last updated on: 2017-05-30
Independence of Group Elements and Geometric Rigidity
ID: 203418
Start date: 2008-07-01, End date: 2013-12-31
The proposed research contains two main directions in group theory and geometry: Independence of Group Elements and Geometric Rigidity. The first consists of problems related to the existence of free subgroups, uniform and effective ways of producing such, and analogous quest...
Programme: FP7-IDEAS-ERC
Record Number: 87398
Last updated on: 2017-05-30
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List retrieved on: 2018-07-22
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