Community Research and Development Information Service - CORDIS

Horizon 2020 project information and now also report summaries are available on CORDIS. All H2020 projects can be downloaded from the EU Open Data Portal .

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Control mechanisms that pattern microtubules for switching cell division planes during plant morphogenesis
ID: 310068
Start date: 2013-01-01, End date: 2017-12-31
Oriented cell divisions dictate morphogenesis by shaping tissues and organs of multicellular organisms. Oriented cell divisions have profound influence in plants because their cell positions are locked by shared cell walls. A relay of cell divisions involving precise division...
Programme: FP7-IDEAS-ERC
Record Number: 106737
Last updated on: 2016-12-05
Counteracting psychosis by optimizing interaction
ID: 309767
Start date: 2013-04-01, End date: 2018-03-31
Psychotic disorders are amongst the most severe mental disorders. However, current treatments have failed to reduce disability or change the prospects for recovery for patients with a psychotic disorder. In this project, I will investigate an entirely novel therapy, targeting...
Programme: FP7-IDEAS-ERC
Record Number: 107974
Last updated on: 2016-08-15
Reverse engineering of vascular patterning through mosaic in vivo analysis of endothelial cell shape regulation
ID: 311719
Start date: 2012-10-01, End date: 2017-09-30
Current angiogenesis research using genetic loss-of function approaches in mouse and zebrafish models provides for a growing number of genes implicated in blood vessel formation. Mechanistic insight often remains unsatisfactory as phenotypes fall into common categories. Our r...
Programme: FP7-IDEAS-ERC
Record Number: 105258
Last updated on: 2016-03-31
Uncovering the role of new synaptic adhesion molecules in encoding synaptic connectivity in the brain
ID: 311083
Start date: 2013-02-01, End date: 2018-01-31
Synapses connect neurons into a network that encodes our thoughts, memories and personalities. Loss of synaptic connectivity is thought to underlie a variety of cognitive disorders such as autism, schizophrenia and Alzheimer’s disease, but little is known about the molecules ...
Programme: FP7-IDEAS-ERC
Record Number: 106739
Last updated on: 2016-03-31
The role of loss-of-heterozygosity in cancer development and progression
ID: 310368
Start date: 2012-10-01, End date: 2017-09-30
Somatically acquired loss-of-heterozygosity (LOH) is extremely common in cancer; deletions of recessive cancer genes, miRNAs, and regulatory elements, can confer selective growth advantage, whereas deletions over fragile sites are thought to reflect an increased local rate of...
Programme: FP7-IDEAS-ERC
Record Number: 105329
Last updated on: 2016-03-31
Oxygen sensing in macrophages: implications for cancer and ischemia
ID: 308459
Start date: 2012-11-01, End date: 2017-10-31
Macrophages exist in distinct differentiation states. Proangiogenic/immunosuppressive (M2-like) macrophages and antitumoral/proinflammatory (M1-like) macrophages represent two extremities of a continuum. Because lineage-defined subsets have not been identified yet, macrophage...
Programme: FP7-IDEAS-ERC
Record Number: 105420
Last updated on: 2016-03-31
ID: 311725
Start date: 2013-01-01, End date: 2017-12-31
"Excessive delays in treatment onset limit current tuberculosis (TB) control programs, presenting a major obstacle to the control of the TB epidemic. Increasing case detection, both quantitatively and temporally, is considered a priority, benefiting the patient (reduced morbi...
Programme: FP7-IDEAS-ERC
Record Number: 106459
Last updated on: 2015-03-11
Unravelling environmental exposures 
in the core axis of ageing
ID: 310898
Start date: 2013-03-01, End date: 2018-02-28
"AGEing is a complex phenotype responsive to a plethora of ENVIRONmental inputs (ENVIRONAGE). Age related conditions in adults often find their origin in risk factors operative in early life. The molecular mechanisms behind these phenomena remain largely unknown. Mitochondria...
Programme: FP7-IDEAS-ERC
Record Number: 107400
Last updated on: 2015-03-11
ID: 309792
Start date: 2013-05-01, End date: 2018-04-30
"Bicuspid aortic valve, a heart valve with only two leaflets instead of three, is the most common congenital heart defect with an estimated prevalence of about 1-2%. The heart defect often remains asymptomatic but in at least 10% of the bicuspid aortic valve patients, an asce...
Programme: FP7-IDEAS-ERC
Record Number: 107846
Last updated on: 2015-03-11
Starting an electrical conversation between microorganisms and electrodes to achieve bioproduction
ID: 310023
Start date: 2012-10-01, End date: 2017-09-30
"Electrochemically active bacteria enable a host of novel processes in bioproduction, bioenergy and bioremediation. Key to the success of these processes is effective adherence of the bacterial cells to an electrode surface and subsequent equally effective electron exchange w...
Programme: FP7-IDEAS-ERC
Record Number: 105101
Last updated on: 2015-03-11
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List retrieved on: 2018-05-28
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