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Horizon 2020 project information and now also report summaries are available on CORDIS. All H2020 projects can be downloaded from the EU Open Data Portal .

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The role of CpG island RNAs and Polycomb-RNA interactions in developmental gene regulation
ID: 311704
Start date: 2013-09-01, End date: 2019-04-30
A great challenge in developmental biology research has been to understand how cell type specific expression programs are orchestrated through regulated access to chromatin. The interaction between non-coding RNAs and chromatin regulators is emerging as an exciting new resear...
Programme: FP7-IDEAS-ERC
Record Number: 109713
Last updated on: 2018-01-03
The Origin of Jawed Vertebrates and the Evolution of Morphology in Deep Time
ID: 311092
Start date: 2013-01-01, End date: 2018-12-31
Jawed vertebrates account for more than 99% of modern vertebrate diversity. Collectively, they comprise chondrichthyans (sharks, rays, and chimaeras) and osteichthyans (bony fishes and terrestrial vertebrates, including humans). The anatomy of jawed vertebrates includes a ser...
Programme: FP7-IDEAS-ERC
Record Number: 105578
Last updated on: 2017-12-18
Priming of plant immunity: from its onset to trans-generational maintenance
ID: 309944
Start date: 2013-01-01, End date: 2017-12-31
Plant defence depends on speed: the sooner a plant recognises its attacker, the more effective its defence response will be. Over the course of evolution, plants have acquired the ability to prime their immune system after perception of specific environmental signals. This he...
Programme: FP7-IDEAS-ERC
Record Number: 104861
Last updated on: 2017-12-18
The analysis of mitochondrial dynamics in ageing and neurodegeneration
ID: 309742
Start date: 2013-01-01, End date: 2018-12-31
The survival of our most active tissues, such as the brain and heart, throughout decades of a human lifespan presents an extraordinary biological challenge. Mitochondria are central to the life and death of these tissues. They provide the cellular energy required by these cel...
Programme: FP7-IDEAS-ERC
Record Number: 105785
Last updated on: 2017-12-11
Regulation of Chromatin by Combinatorial DNA and Histone Modifications
ID: 309952
Start date: 2013-05-01, End date: 2019-04-30
The normal expression of genes is tightly regulated. Modifications on histones or on DNA play a central role in the control of gene expression and errors in their regulation often result in diseases such as cancer. These modifications can recruit proteins that regulate chroma...
Programme: FP7-IDEAS-ERC
Record Number: 107360
Last updated on: 2017-11-20
Definition and characterization of type I interferonopathies
ID: 309449
Start date: 2013-03-01, End date: 2018-10-31
Although the concept of grouping Mendelian disorders associated with an up-regulation of type I interferon (IFN) has not been previously recognised in the medical literature, my past and current work argues that this concept has scientific validity and clinical utility. I bel...
Programme: FP7-IDEAS-ERC
Record Number: 107398
Last updated on: 2017-11-20
Molecular determinants of aphid host range
ID: 310190
Start date: 2013-02-01, End date: 2018-10-31
Many aphid species are restricted to one or few host plants, while some aphids, many of which are of agricultural importance, can infest a wide range of plant species. An important observation is that aphids spend a considerable time on nonhost species, where they probe the l...
Programme: FP7-IDEAS-ERC
Record Number: 105786
Last updated on: 2017-11-20
Investigating Hereditary Cancer Predisposition – a combined genomics approach
ID: 310018
Start date: 2013-05-01, End date: 2019-04-30
Background: Hereditary cancer is an important cause of morbidity and mortality and over the last 20 years, the majority of highly penetrant risk alleles such as BRCA1, BRCA2 in breast cancer and APC, MLH1, MSH2 in colon cancer have been identified. However, there are many men...
Programme: FP7-IDEAS-ERC
Record Number: 108266
Last updated on: 2017-11-20
Protection against reactive oxygen species in neurodegeneration
ID: 311394
Start date: 2013-02-01, End date: 2018-05-31
Oxidative stress (OS) is implicated in the pathogenesis of some of the most devastating neurological diseases. Therefore, identification of pathways that counteract oxidative damage may lead to therapeutic strategies applicable to a wide range of disorders. I have recently id...
Programme: FP7-IDEAS-ERC
Record Number: 106704
Last updated on: 2017-09-24
Molecular Mechanisms of GABAergic synapse formation: spatial segregation in cortical inhibitory inputs
ID: 310021
Start date: 2013-01-01, End date: 2018-06-30
Neuronal circuitries underlying the function of the mammalian cerebral cortex collectively constitute one of the most complex biological systems. As such, unraveling the mechanisms that control their development represents one of the most challenging questions in Science. Und...
Programme: FP7-IDEAS-ERC
Record Number: 105616
Last updated on: 2017-09-24
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List retrieved on: 2018-06-24
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