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FP7-IDEAS-ERC (6)

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Results 1 - 6 of 6
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1
Coevolution of bacteria and conjugative plasmids
ID: 311490
Start date: 2013-02-01, End date: 2018-01-31
Horizontal gene transfer (HGT) is a fundamental process of bacterial evolution, accelerating adaptation to novel environments and providing access to new ecological niches. However, two of the three mechanisms of HGT, transduction and conjugation, both rely on semi-autonomous...
Programme: FP7-IDEAS-ERC
Record Number: 105951
Last updated on: 2017-05-22
The interaction landscape between microbial colonization and functional genome of the host: a systems biology approach in fungal infections
ID: 310372
Start date: 2013-01-01, End date: 2017-12-31
Fungi such as Candida albicans are ubiquitous colonizers of human skin and mucosa. Fungal pathogens invade the host when host defence is diminished, and the combination of fungal and bacterial colonization modulates mucosal and systemic immune responses. Little is known of th...
Programme: FP7-IDEAS-ERC
Record Number: 105950
Last updated on: 2017-05-08
Ancient Pathogen Genomics of Re-Emerging Infectious Disease
ID: 310920
Start date: 2013-01-01, End date: 2017-12-31
Here we propose a first step toward a direct reconstruction of the evolutionary history of human infectious disease agents by obtaining genome wide data of historic pathogens. Through an extensive screening of skeletal collections from well-characterized catastrophe, or emerg...
Programme: FP7-IDEAS-ERC
Record Number: 104863
Last updated on: 2016-07-18
Inborn errors of innate immunity: systems genomics route to the core of the immune system
ID: 310857
Start date: 2013-11-01, End date: 2018-10-31
The ultimate relevance of a component of the innate immune system in human physiology is uncovered by the consequence of mutations in the associated gene. We have integrated systems genomics tools to mine, uncover and pathway-map primary deficiencies with high efficiency. Pri...
Programme: FP7-IDEAS-ERC
Record Number: 110847
Last updated on: 2016-03-31
Unravelling paradoxes in regulatory T cell biology: the molecular basis for an mTOR-dependent oscillatory metabolic switch controlling immune tolerance and autoimmunity
ID: 310496
Start date: 2013-05-01, End date: 2018-04-30
Our group has been investigating how the nutrient/energy-sensing mammalian target of rapamycin (mTOR)-pathway affects the responsiveness of CD4+CD25+FoxP3+ regulatory T cells (Tregs). We have shown that Tregs have a high metabolic profile associated with the hyperactivation o...
Programme: FP7-IDEAS-ERC
Record Number: 108004
Last updated on: 2016-03-31
Social development and life history evolution in cooperative mammals: an integrated approach
ID: 309249
Start date: 2013-01-01, End date: 2017-12-31
"Studies of cooperative animal societies have advanced understanding of social evolution but have also revealed great individual variation in cooperative behaviour and major life history traits, even among individuals of the same age, sex and social status. Research on labora...
Programme: FP7-IDEAS-ERC
Record Number: 106436
Last updated on: 2015-03-11
1
List retrieved on: 2018-06-22
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