Community Research and Development Information Service - CORDIS

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Proteomic prediction and Renin angiotensin aldosterone system Inhibition prevention Of early diabetic nephRopathy In TYpe 2 diabetic patients with normoalbuminuria
ID: 279277
Start date: 2012-01-01, End date: 2018-12-31
Patients with diabetes are at risk of developing diabetic nephropathy, which will ultimately result in the requirement for renal replacement therapy and is also associated with high cardiovascular morbidity and mortality. Detection of low concentrations of albuminuria in urin...
Programme: FP7-HEALTH
Record Number: 101813
Last updated on: 2018-01-22
Systems Biology to Identify Molecular Targets for Vascular Disease Treatment
ID: 603288
Start date: 2014-02-01, End date: 2018-01-31
Asymptomatic vascular damage accumulates for years before patients are identified and subjected to therapeutic measures. The limited knowledge on early vascular disease pathophysiology is reflected in the lack of therapeutic options. SysVasc aims to overcome this limitation b...
Programme: FP7-HEALTH
Record Number: 111200
Last updated on: 2018-01-03
New Medicines for Trypanosomatidic Infections
ID: 603240
Start date: 2014-02-01, End date: 2017-01-31
The infectious diseases burden imposed by the parasites of Trypanosomatidae family represents a huge problem on people’s lives in countries where these diseases are endemic. Problems associated with existing drugs include inefficient delivery, insufficient efficacy, excessive...
Programme: FP7-HEALTH
Record Number: 109924
Last updated on: 2018-01-03
Development of COMBInatorial BIOmarkers for subclinical atherosclerosis
ID: 305422
Start date: 2012-10-01, End date: 2014-09-30
Systems biology involves the analysis of relationships among the elements in a system, viewed as an integrated and interacting network of genes, proteins and biochemical reactions. We have pioneered the use of metabolic profiling and the metabolome-wide association study (MWA...
Programme: FP7-HEALTH
Record Number: 105394
Last updated on: 2017-12-18
A novel drug discovery method based on systems biology: combination therapy and biomarkers for Multiple Sclerosis
ID: 305397
Start date: 2013-01-01, End date: 2014-12-31
The therapeutic challenge of complex diseases requires the use of combination therapies to target the distinct mechanisms and pathways involved. Such complex diseases will benefit from the design of computational models adopting a systems perspective to integrate the knowledg...
Programme: FP7-HEALTH
Record Number: 106479
Last updated on: 2017-12-18
Better Experimental Screening and Treatment for Primary Ciliary Dyskinesia
ID: 305404
Start date: 2012-12-01, End date: 2016-05-31
Primary Ciliary Dyskinesia (PCD) is a rare genetically heterogeneous disorder which results from dysfunction of motile hair-like organelles (cilia) that results in severe, chronic airways disease. Due to other cilia-related disease mechanisms several other organ systems like ...
Programme: FP7-HEALTH
Record Number: 106177
Last updated on: 2017-12-11
European Asthma Research and Innovation Partnership
ID: 602077
Start date: 2013-09-01, End date: 2016-08-31
Europe has 30 million people with asthma, whose treatment costs about €20 bn annually. Productivity lost through poor asthma control in Europe is estimated to be €9.8 bn per year. By 2020 approximately 120,000 people in Europe will die from asthma attacks, and 4 million hospi...
Programme: FP7-HEALTH
Record Number: 109334
Last updated on: 2017-12-07
Translation of novel Biomarkers for Bladder Cancer for clinical outcome prediction
ID: 601933
Start date: 2013-09-01, End date: 2016-08-31
Currently, clinical diagnosis and monitoring of bladder cancer (BC) relies on invasive, highly costly cystoscopy. Additionally, due to high recurrence rates BC treatment is associated with frequent follow-up of patients, making BC one of the most costly types of cancer in ter...
Programme: FP7-HEALTH
Record Number: 110337
Last updated on: 2017-12-07
Crimean Congo Hemorrhagic Fever; Modern Approaches to  Diagnostics, Surveillance, Prevention, Therapy and Preparedness
ID: 260427
Start date: 2010-10-01, End date: 2015-03-31
Over the last years, large outbreaks of Crimean Congo Hemorrhagic fever virus (CCHFV) in several European countries and neighbouring areas are on the rise. This disease poses a great threat to public health due to its high mortality rate, modes of transmission and geographica...
Programme: FP7-HEALTH
Record Number: 96779
Last updated on: 2017-12-04
Early Prevention of Diabetes Complications in people with Hyperglycaemia in Europe
ID: 279074
Start date: 2012-01-01, End date: 2017-12-31
"Background: A significant proportion of pre-diabetics, show macro and micro vascular complications associated with hyperglycaemia. Although many trials have demonstrated the efficacy of lifestyle and pharmaceutical interventions in diabetes prevention, no trial has evaluated...
Programme: FP7-HEALTH
Record Number: 101998
Last updated on: 2017-11-20
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List retrieved on: 2018-05-23
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