Community Research and Development Information Service - CORDIS

Horizon 2020 project information and now also report summaries are available on CORDIS. All H2020 projects can be downloaded from the EU Open Data Portal .

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Clinical safety, immunogenicity and efficacy of a therapeutic vaccine that combines peptides mimicking antigen receptors on autoimmune B and T cells associated with myasthenia gravis
ID: 602420
Start date: 2013-10-01, End date: 2018-09-30
The MYASTERIX project will advance a therapeutic vaccine candidate (designated orphan drug) indicated for the autoimmune disease myasthenia gravis (MG) to clinical proof of concept studies. MG is caused by T cell dependent antibodies that bind to and deplete acetylcholine rec...
Programme: FP7-HEALTH
Record Number: 110173
Last updated on: 2016-03-31
Nano Engineering for Cross Tolerance: new approach for bioengineered, vascularised, chimeric islet transplantation in non-immunosuppressed hosts
ID: 602235
Start date: 2013-10-01, End date: 2017-09-30
Diabetes is caused by insufficient or lack of insulin secretion by the specialized B cells of the pancreas and, if not treated adequately evolves into in complications which alter patients integrity and wellness. Treatment is based on lifetime drugs administration for blood g...
Programme: FP7-HEALTH
Record Number: 110189
Last updated on: 2018-01-03
A “Universal” Influenza Vaccine through Synthetic, Dendritic Cell-Targeted, Self-Replicating RNA Vaccines
ID: 601738
Start date: 2013-10-01, End date: 2018-09-30
Although vaccination is the cornerstone of prophylaxis, current vaccines provide only moderate protection. Most employ inactivated or protein-based, including multimeric antigen, vaccines requiring annual updating. Their limited antigen loads provide limited capacity for indu...
Programme: FP7-HEALTH
Record Number: 109454
Last updated on: 2016-03-31
IMAging GEnetics for MENtal Disorders
ID: 602450
Start date: 2013-10-01, End date: 2017-09-30
Mental disorders are leading causes of disability, absence from work and premature retirement in Europe. While magnetic resonance imaging (MRI) facilities are broadly available and a vast research literature exists, few neuroimaging applications have reached clinical practice...
Programme: FP7-HEALTH
Record Number: 109465
Last updated on: 2017-12-07
Comparative Effectiveness Research to Assess the Use of Primary ProphylacTic Implantable Cardioverter Defibrillators in EUrope
ID: 602299
Start date: 2013-10-01, End date: 2018-09-30
An estimated 500.000 sudden cardiac deaths (SCD) occur each year in the European Union. Patients at risk for SCD may benefit from prophylactic treatment with an implantable cardioverter-defibrillator (ICD). ICD implantations have dramatically increased in recent years leading...
Programme: FP7-HEALTH
Record Number: 110067
Last updated on: 2017-06-26
Optimizing Exercise Training in Prevention and Treatment of Diastolic Heart Failure
ID: 602405
Start date: 2013-10-01, End date: 2017-09-30
More than 14 million Europeans suffer from heart failure (HF), of which more than 50 % have HF with preserved left ventricular (LV) ejection fraction (EF) (HFPEF, “diastolic heart failure”). HFPEF is the only cardiovascular disease with increasing prevalence and incidence, af...
Programme: FP7-HEALTH
Record Number: 110069
Last updated on: 2017-01-30
Treating stroke with Affibody molecules targeting the inflammatory mediator HMGB1
ID: 602354
Start date: 2013-10-01, End date: 2018-09-30
The scope of the project is to generate a candidate drug targeting the inflammatory mediator High mobility group box 1 protein (HMGB1) to be used in treatment of stroke. The candidate drug will be validated in animal models, characterized and optimized for subsequent clinical...
Programme: FP7-HEALTH
Record Number: 110068
Last updated on: 2016-08-08
Systems biology for the functional validation of genetic determinants of skeletal diseases
ID: 602300
Start date: 2013-10-01, End date: 2018-09-30
"The aim of SYBIL is to carry out extensive functional validation of the genetic determinants of rare and common skeletal diseases and the age related factors contributing to these painful conditions. To achieve this goal SYBIL will gather complementary translational and tran...
Programme: FP7-HEALTH
Record Number: 109342
Last updated on: 2015-03-11
Cell-based regenerative medicine: new challenges for EU legislation and governance
ID: 601806
Start date: 2013-10-01, End date: 2016-09-30
This proposal aims at collecting and analysing facts and figures in order to assess the current legislation on the therapeutic use of somatic cells, and to bridge it with the research infrastructure capacity building. Although EU has adopted 3 Directives on Tissues and cells ...
Programme: FP7-HEALTH
Record Number: 109331
Last updated on: 2016-03-31
Human pluripotent stem cell differentiation, safety and preparation for therapeutic transplantation in Huntington’s disease
ID: 602245
Start date: 2013-10-01, End date: 2018-03-31
This project will tackle the huge complexity of taking stem cell therapies to clinical application for neurodegenerative disease by focusing on selective differentiation of a single neuronal phenotype (medium spiny striatal neuron: MSN) for a single well-defined disease (Hunt...
Programme: FP7-HEALTH
Record Number: 109572
Last updated on: 2017-12-11
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List retrieved on: 2018-05-25
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