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Le informazioni sui progetti di Orizzonte 2020 e ora anche le relative sintesi delle relazioni sono disponibili su CORDIS. Tutti i progetti H2020 possono essere scaricati dal Portale Open Data dell'UE .

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Results 71 - 80 of 1008
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A drug strategy targeting stabilised mutant p53 to fight metastatic platinum-resistant ovarian cancer
ID: 602602
Data di inizio: 2013-10-01, Termine: 2019-03-31
"Epithelial ovarian cancer (EOC) is the most lethal gyncaecological malignancy causing 41900 deaths annually in Europe. The predominance of aggressive Type II tumours, which are characterised by a high frequency of p53 mutations, and primary or acquired resistance to platinum...
Programme: FP7-HEALTH
Record Number: 110338
Last updated on: 2015-03-11
Health and the Understanding of Metabolism, Aging and Nutrition
ID: 602757
Data di inizio: 2013-10-01, Termine: 2018-09-30
Recently intense research identified around 4,000 single nucleotide polymorphisms (SNPs) associated with human age related diseases such as metabolic disorders. Despite their highly significant association to pathology, the functional role of these genetic variants is, in mos...
Programme: FP7-HEALTH
Record Number: 110177
Last updated on: 2017-11-20
Clinical safety, immunogenicity and efficacy of a therapeutic vaccine that combines peptides mimicking antigen receptors on autoimmune B and T cells associated with myasthenia gravis
ID: 602420
Data di inizio: 2013-10-01, Termine: 2018-09-30
The MYASTERIX project will advance a therapeutic vaccine candidate (designated orphan drug) indicated for the autoimmune disease myasthenia gravis (MG) to clinical proof of concept studies. MG is caused by T cell dependent antibodies that bind to and deplete acetylcholine rec...
Programme: FP7-HEALTH
Record Number: 110173
Last updated on: 2016-03-31
Nano Engineering for Cross Tolerance: new approach for bioengineered, vascularised, chimeric islet transplantation in non-immunosuppressed hosts
ID: 602235
Data di inizio: 2013-10-01, Termine: 2017-09-30
Diabetes is caused by insufficient or lack of insulin secretion by the specialized B cells of the pancreas and, if not treated adequately evolves into in complications which alter patients integrity and wellness. Treatment is based on lifetime drugs administration for blood g...
Programme: FP7-HEALTH
Record Number: 110189
Last updated on: 2018-01-03
A “Universal” Influenza Vaccine through Synthetic, Dendritic Cell-Targeted, Self-Replicating RNA Vaccines
ID: 601738
Data di inizio: 2013-10-01, Termine: 2018-09-30
Although vaccination is the cornerstone of prophylaxis, current vaccines provide only moderate protection. Most employ inactivated or protein-based, including multimeric antigen, vaccines requiring annual updating. Their limited antigen loads provide limited capacity for indu...
Programme: FP7-HEALTH
Record Number: 109454
Last updated on: 2016-03-31
IMAging GEnetics for MENtal Disorders
[PROGETTO] IMAGEMEND - IMAging GEnetics for MENtal Disorders
ID: 602450
Data di inizio: 2013-10-01, Termine: 2017-09-30
Mental disorders are leading causes of disability, absence from work and premature retirement in Europe. While magnetic resonance imaging (MRI) facilities are broadly available and a vast research literature exists, few neuroimaging applications have reached clinical practice...
Programme: FP7-HEALTH
Record Number: 109465
Last updated on: 2017-12-07
Comparative Effectiveness Research to Assess the Use of Primary ProphylacTic Implantable Cardioverter Defibrillators in EUrope
ID: 602299
Data di inizio: 2013-10-01, Termine: 2018-09-30
An estimated 500.000 sudden cardiac deaths (SCD) occur each year in the European Union. Patients at risk for SCD may benefit from prophylactic treatment with an implantable cardioverter-defibrillator (ICD). ICD implantations have dramatically increased in recent years leading...
Programme: FP7-HEALTH
Record Number: 110067
Last updated on: 2017-06-26
Optimizing Exercise Training in Prevention and Treatment of Diastolic Heart Failure
ID: 602405
Data di inizio: 2013-10-01, Termine: 2017-09-30
More than 14 million Europeans suffer from heart failure (HF), of which more than 50 % have HF with preserved left ventricular (LV) ejection fraction (EF) (HFPEF, “diastolic heart failure”). HFPEF is the only cardiovascular disease with increasing prevalence and incidence, af...
Programme: FP7-HEALTH
Record Number: 110069
Last updated on: 2017-01-30
Treating stroke with Affibody molecules targeting the inflammatory mediator HMGB1
ID: 602354
Data di inizio: 2013-10-01, Termine: 2018-09-30
The scope of the project is to generate a candidate drug targeting the inflammatory mediator High mobility group box 1 protein (HMGB1) to be used in treatment of stroke. The candidate drug will be validated in animal models, characterized and optimized for subsequent clinical...
Programme: FP7-HEALTH
Record Number: 110068
Last updated on: 2016-08-08
Systems biology for the functional validation of genetic determinants of skeletal diseases
ID: 602300
Data di inizio: 2013-10-01, Termine: 2018-09-30
"The aim of SYBIL is to carry out extensive functional validation of the genetic determinants of rare and common skeletal diseases and the age related factors contributing to these painful conditions. To achieve this goal SYBIL will gather complementary translational and tran...
Programme: FP7-HEALTH
Record Number: 109342
Last updated on: 2015-03-11
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List retrieved on: 2018-06-22