Cel Many common diseases currently require that samples be sent to remote labs for diagnosis. This is costly and takes time, increasing patient anxiety and delaying the start of treatment. This project will make it feasible to carry out automatic, accurate diagnosis at the local doctor's office. This will be achieved using bio-marker mRNA detection. Compared to commonly used approaches, mRNA detection avoids false positive results and has a high sensitivity. It can currently be used to detect cancer and a range of respiratory diseases, to mention a few. New bio-markers are developed every day. The partners have already developed prototype technology which partly demonstrates a microsystem operation of the mRNA approach.The project will build on this, providing the innovation needed to transform a promising technology to an integrated system suitable for practical use at point-of-care:- Provide support for all stages: cell concentration, lysis, purification, sample collection, reagent mixing, amplification and detection.-Develop disposable polymer chips for use in the portable instrument, including technology for storing all needed reagents on these chips.-Develop reliable techniques for multi-channel parallel detection (crucial for recognising disease signatures).-Address factors such as reliability, usability and cost which are crucial to acceptance by health care professionals.System accuracy will be validated on the specific case of HPV (the virus causing cervical cancer), by comparing with macroscopic results and alternative methods used at laboratories. The consortium includes two research institutes and two industrial firms (both SMEs), who have extensive experience with mRNA techniques, and are motivated to commercialise results. They will be assisted by a hospital acting as end user, validating system usability and clinical accuracy. Dziedzina nauki natural sciencesbiological sciencesmicrobiologyvirologynatural scienceschemical sciencespolymer sciencesmedical and health scienceshealth sciencesinfectious diseasesRNA virusescoronavirusesmedical and health sciencesclinical medicineoncologycervical cancermedical and health scienceshealth sciencesinfectious diseasesDNA viruses Słowa kluczowe Nanotechnology Program(-y) FP6-NMP - Nanotechnologies and nanosciences, knowledge-based multifunctional materials and new production processes and devices: thematic priority 3 under the 'Focusing and integrating community research' of the 'Integrating and strengthening the European Research Area' specific programme 2002-2006. Temat(-y) NMP-2004-IST-NMP-2 - Bio-sensors for Diagnosis and Healthcare Zaproszenie do składania wniosków Data not available System finansowania STREP - Specific Targeted Research Project Koordynator STIFTELSEN SINTEF Wkład UE Brak danych Adres Strindveien 4 7465 TRONDHEIM Norwegia Zobacz na mapie Koszt całkowity Brak danych Uczestnicy (5) Sortuj alfabetycznie Sortuj według wkładu UE Rozwiń wszystko Zwiń wszystko ALBERT-LUDWIGS-UNIVERSITAET FREIBURG Niemcy Wkład UE Brak danych Adres FAHNENBERGPLATZ 79085 FREIBURG Zobacz na mapie Koszt całkowity Brak danych BIOFLUIDIX GMBH Niemcy Wkład UE Brak danych Adres GEORGE-KOEHLER-ALLEE 106 79110 FREIBURG Zobacz na mapie Koszt całkowity Brak danych INSTITUT FUER MIKROTECHNIK MAINZ GMBH Niemcy Wkład UE Brak danych Adres CARL-ZEISS-STRASSE 18-20 55129 MAINZ Zobacz na mapie Koszt całkowity Brak danych NORCHIP AS Norwegia Wkład UE Brak danych Adres INDUSTRIEVEIEN 8 3490 KLOKKARSTUA Zobacz na mapie Koszt całkowity Brak danych THE COOMBE WOMEN'S HOSPITAL Irlandia Wkład UE Brak danych Adres DOLPHINS BARN ROAD - CORK STREET DUBLIN 8 Zobacz na mapie Koszt całkowity Brak danych