Objective Post-genomic structural biology can advance understanding of biological systems by exploiting genomic data, making use of high-throughput methods, integrating techniques across structural scales and closely integrating with functional studies. Based on the se principles, a new infrastructure, the Centre for Integrated Structural Biology (CISB) will combine resources of three leading international institutes, the European Molecular Biology Laboratory, the European Synchrotron Radiation Facility and the Instit ut Laue-Langevin together with the Universit Joseph Fourier, Grenoble representing both the French Institut de Biologie Structural and the Institut de Virologie Molculaire et Structurale. The CISB will be unique in Europe in combining on the same Grenoble site: (i) state-of-the-art European facilities for synchrotron X-ray and neutron macromolecular crystallography and small angle scattering, (ii) expertise in automation, instrumentation and methods development for structural biology, (iii) complementary st ructural biologytechniques such as NMR, electron microscopy, molecular biology and biochemistry, (iv) strong structure-orientated research projects in a broad range of molecular and cell biology and with an increasing focus on human health, particularly vi rology, (v) Numerous links to the European scientific and industrial community through European networks of excellence, research collaborations, provision of user facilities and training. A new CISB laboratory complex will be built for scientists from all partners. New technical platforms will be established for high throughput protein expression and crystallisation, protein sample quality control, in vivo isotope labelling, high-throughput X-ray crystallographic data collection, neutron crystallography and electron microscopy. The CISB will stimulate multidisciplinary research in structural biology both locally and Europe wide, thus representing an important integrative step in structuring the European researc Fields of science natural sciencesearth and related environmental sciencesgeologymineralogycrystallographynatural sciencesbiological sciencesbiochemistrybiomoleculesproteinsnatural sciencesbiological sciencescell biologynatural sciencesphysical sciencesopticsmicroscopyelectron microscopynatural sciencesbiological sciencesmolecular biologystructural biology Programme(s) FP6-INFRASTRUCTURES - Research infrastructures: Specific programme for research, technological development and demonstration: "Structuring the European Research Area" under the Sixth Framework Programme 2002-2006 Topic(s) INFRASTR-5 - Construction of new infrastructures: optimising of European infrastructures by providing limited support in duly justified cases, alongside with other funding agencies Call for proposal FP6-2003-INFRASTRUCTURES-4 See other projects for this call Funding Scheme CNI-SSA - Construction of new infrastructures implemented as Specific Support Actions Coordinator EUROPEAN MOLECULAR BIOLOGY LABORATORY EU contribution No data Address Meyerhofstrasse 1 HEIDELBERG Germany See on map Links Website Opens in new window Total cost No data Participants (3) Sort alphabetically Sort by EU Contribution Expand all Collapse all EUROPEAN SYNCHROTRON RADIATION FACILITY France EU contribution No data Address 6, RUE JULES HOROWITZ PO Box 220 GRENOBLE See on map Links Website Opens in new window Total cost No data INSTITUT MAX VON LAUE - PAUL LANGEVIN France EU contribution No data Address 6 Rue Jules Horowitz PO Box 156 GRENOBLE See on map Links Website Opens in new window Total cost No data UNIVERSITE JOSEPH FOURIER GRENOBLE 1 France EU contribution No data Address 621 Avenue Centrale - Domaine universitaire PO Box 53 GRENOBLE See on map Links Website Opens in new window Total cost No data
