Objectif Biochip technology allows assessing the expression of thousands of genes in parallel, opening the way to individualised healthcare. The INDIGO project will replace the current bulky and expensive technology used to hybridise and read fluorescent biochips by a lab-on-chip approach, with integrated signal processing and networking capacities. The project reconsiders the complete biochip user chain, and optimises each component in relation to others.At the core of INDIGO is an innovative, miniature and highly sensitive, yet disposable fluorescence-based biosensor. It replaces the usual glass slide supporting the biological reaction by a sandwich of chemical and optical layers monolithically grafted on a CMOS or CCD image sensor. Intermediate layers play an essential optical role for guiding and filtering light. The upper side of the sensor is devoted to biology, the lower side to imaging by direct, and efficient light collection by the pixels. Improving signal level will enhance the sensitivity and robustness of the biological measurements.Such a lensless imaging device produces images with new characteristics and needs development of new data processing software. The image produced by the sensor will be read in a laptop-connected readout head, and then filtered, segmented and measured; the results will be normalised, written in a standard format, ready to be recorded into a database or transmitted through networks.With its user-friendly interface, the system will undergo clinical validation in biology labs, on samples from patients with different cancers and cardiovascular diseases. The INDIGO project is well suited to the joint IST and NMP call on biosensors for Diagnosis and Healthcare. On the NMP side, smart and hybrid materials like sol-gels with extreme characteristics, able to be industrially coated, as thin layers will be developed. On the IST side, new data treatment chain will give standardised biological data usable by the medical community at large. Champ scientifique engineering and technologyelectrical engineering, electronic engineering, information engineeringelectronic engineeringsensorsbiosensorsengineering and technologyelectrical engineering, electronic engineering, information engineeringelectronic engineeringsensorsoptical sensorsengineering and technologyelectrical engineering, electronic engineering, information engineeringelectronic engineeringsignal processingmedical and health sciencesclinical medicinecardiologycardiovascular diseasesnatural sciencescomputer and information sciencesdata sciencedata processing Programme(s) FP6-NMP - Nanotechnologies and nanosciences, knowledge-based multifunctional materials and new production processes and devices: thematic priority 3 under the 'Focusing and integrating community research' of the 'Integrating and strengthening the European Research Area' specific programme 2002-2006. Thème(s) Data not available Appel à propositions Data not available Régime de financement STREP - Specific Targeted Research Project Coordinateur ATMEL-Grenoble SAS Contribution de l’UE Aucune donnée Adresse Avenue de Rochepleine 123 SAINT EGREVE France Voir sur la carte Coût total Aucune donnée Participants (5) Trier par ordre alphabétique Trier par contribution de l’UE Tout développer Tout réduire ASSOCIATION POUR LA RECHERCHE ET LE DEVELOPPEMENT DES METHODES ET PROCESSUS INDUSTRIELS France Contribution de l’UE Aucune donnée Adresse 60, BOULEVARD SAINT-MICHEL PARIS Voir sur la carte Coût total Aucune donnée Consorzio Interuniversitario Nazionale per la Scienza e Tecnologia dei Materiali Italie Contribution de l’UE Aucune donnée Adresse Via Benedetto Varchi, 59 FIRENZE Voir sur la carte Coût total Aucune donnée FUNDACIÓN VALENCIANA DE INVESTIGACIONES BIOMÉDICAS Espagne Contribution de l’UE Aucune donnée Adresse AVDA. AUTOPISTA DEL SALER, NÚM. 16 VALENCIA Voir sur la carte Coût total Aucune donnée Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III Espagne Contribution de l’UE Aucune donnée Adresse SINESIO DELGADO, 6 MADRID Voir sur la carte Coût total Aucune donnée GENEWAVE France Contribution de l’UE Aucune donnée Adresse 4 RUE PIERRE FONTAINE 91000 EVRY Voir sur la carte Coût total Aucune donnée