Project description
Personal Health Systems for Monitoring and Point-of-Care diagnostics
The POCEMON project aims to the hardware and software development of a multi-purpose autoimmune diseases diagnostic platform by combining Lab-on-Chip (LOC) technologies, genomic microarrays of HLA (human leukocyte antigens) typing, microelectronics, mobile devices, intelligent algorithms and wireless communications. The multi-purpose platform will be provided as a portable integrated platform with application to primary care level. The final product will be capable to communicate through its PDA device with the Laboratory Information Server (LIS) for detailed analysis, diagnosis and information extraction concerning autoimmune diseases; the LIS will be also developed inside the time-framework of the project. Microelectronics-microfludics for the LOC and robotics for the HLA microarrays' construction, constitute the main state-of-the-art scientific technologies which will be employed for the development of the portable diagnostic genomics laboratory.Autoimmune disorders (diseases) develop when the immune system destroys normal body tissues. HLA genes are the major determinants used by the body's immune system for recognition and differentiation of self from non-self (foreign substances). The combination of LOC technologies with genomic microarrays of HLA typing will provide a state-of-the-art diagnosis at primary care level, concerning multiple sclerosis and rheumatoid arthritis which are linked with the HLA CLASS I and II genes. The development of a primary care diagnostic LOC platform based on microarrays of HLA typing is the main target of this proposed project. Easily adapted developments will lead to the diagnosis on the majority of autoimmune disorders. The POCEMON platform will advance and promote primary health care diagnosis across Europe.
Fields of science
- natural sciencesbiological sciencesgenetics
- medical and health sciencesclinical medicinerheumatology
- natural sciencescomputer and information sciencessoftwaresoftware development
- medical and health sciencesbasic medicineneurologymultiple sclerosis
- medical and health sciencesbasic medicineimmunologyautoimmune diseases
Call for proposal
FP7-ICT-2007-1
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Funding Scheme
CP - Collaborative project (generic)Coordinator
38122 Trento
Italy
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Participants (19)
9020 KLAGENFURT
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2340 MODLING
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9020 Klagenfurt am Wörthersee
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2371 AGIOS DOMETIOS
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170 00 PRAHA 7
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75008 PARIS
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117 42 ATHENS
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45110 Ioannina
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17564 PALAIO FALIRO
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17564 PALAIO FALIRO
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1125 BUDAPEST
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00198 ROMA
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20122 Milano
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13100 Vercelli
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20124 Milano
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20132 MILANO
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10691 Stockholm
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S60 2UD ROTHERHAM
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SW1H 0HW LONDON
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