Objectif The selective functionalization of C-H and C=C bonds remains a formidable unsolved problem, owing to their inert nature. Novel alkane and alkene oxidation reactions exhibiting good and/or unprecedented selectivities will have a big impact on bulk and fine chemistry by opening novel methodologies that will allow removal of protection-deprotection sequences, thus streamlining synthetic strategies. These goals are targeted in this project via design of iron and manganese catalysts inspired by structural elements of the active site of non-heme enzymes of the Rieske Dioxygenase family. Selectivity is pursued via rational design of catalysts that will exploit substrate recognition-exclusion phenomena, and control over proton and electron affinity of the active species. Moreover, these catalysts will employ H2O2 as oxidant, and will operate under mild conditions (pressure and temperature). The fundamental mechanistic aspects of the catalytic reactions, and the species implicated in C-H and C=C oxidation events will also be studied with the aim of building on the necessary knowledge to design future generations of catalysts, and provide models to understand the chemistry taking place in non-heme iron and manganese-dependent oxygenases. Champ scientifique natural scienceschemical scienceselectrochemistryelectrolysisnatural scienceschemical sciencesinorganic chemistrytransition metalsnatural scienceschemical sciencescatalysisnatural sciencesbiological sciencesbiochemistrybiomoleculesproteinsenzymes Mots‑clés green chemistry Programme(s) FP7-IDEAS-ERC - Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Thème(s) ERC-SG-PE5 - ERC Starting Grant - Materials and Synthesis Appel à propositions ERC-2009-StG Voir d’autres projets de cet appel Régime de financement ERC-SG - ERC Starting Grant Institution d’accueil UNIVERSITAT DE GIRONA Contribution de l’UE € 1 299 998,00 Adresse PLACA SANT DOMENEC 3 17004 Girona Espagne Voir sur la carte Région Este Cataluña Girona Type d’activité Higher or Secondary Education Establishments Contact administratif Helena Montiel (Dr.) Chercheur principal Miguel Costas Salgueiro (Dr.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée Bénéficiaires (1) Trier par ordre alphabétique Trier par contribution de l’UE Tout développer Tout réduire UNIVERSITAT DE GIRONA Espagne Contribution de l’UE € 1 299 998,00 Adresse PLACA SANT DOMENEC 3 17004 Girona Voir sur la carte Région Este Cataluña Girona Type d’activité Higher or Secondary Education Establishments Contact administratif Helena Montiel (Dr.) Chercheur principal Miguel Costas Salgueiro (Dr.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée
