Cel Wheat is one of the most important food crops in the world and understanding its genetics and genome organisation is of great value for genetics and plant breeding purposes. Despite is genome complexity (polyploidy), hexaploid and tetraploid wheats behave as diploids during meiosis. This means that each chromosome only recognises its identical (homologue) to pair and not the related chromosomes (homeologues). There are several pairing homologous (Ph) genes controlling chromosome pairing in wheat during meiosis. The strongest effect is associated with the Ph1 locus, which is located on the long arm on chromosome 5B. Ph1 appears to sense homology prior to the chromosomes coming into contact with each other at early meiosis. Thus, if the chromosomes are true homologues, they perfectly recognise each other, chromatin remodelling is synchronized and allows pairing and recombination to occur. If the chromosomes are homoeologous (related), remodelling is not synchronized and the chromosomes fail to pair and recombine. In the absence of Ph1, all chromosomes can remodel without the requirement for the presence of an identical or near identical chromosome, and this increases the chance of pairing between related chromosomes in addition to pairing between true homologues. In this project we want to analyse deeper this Ph1 behaviour and we also want to exploit ph1 mutants as a tool for wheat breeding programs to promote inter-specific recombination between related wild species. In fact, Hordeum chilense (wild barley with interesting agronomic traits for wheat breeding) introgressions will be developed into durum wheat to transfer desirable agronomic traits from this wild barley into wheat, like resistance to diseases or the increment in carotene content. Introgression lines will be crosses with ph1 mutants to promote inter-specific recombination H. chilense-wheat, reduce the size of the H. chilense chromosome fragment. New wheat varieties will be generated. Dziedzina nauki natural sciencesbiological sciencesgeneticshereditynatural sciencesbiological sciencesgeneticschromosomes Program(-y) FP7-IDEAS-ERC - Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Temat(-y) ERC-SG-LS9 - ERC Starting Grant - Applied life sciences and biotechnology Zaproszenie do składania wniosków ERC-2009-StG Zobacz inne projekty w ramach tego zaproszenia System finansowania ERC-SG - ERC Starting Grant Instytucja przyjmująca AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS Wkład UE € 600 000,00 Adres CALLE SERRANO 117 28006 Madrid Hiszpania Zobacz na mapie Region Comunidad de Madrid Comunidad de Madrid Madrid Rodzaj działalności Research Organisations Kierownik naukowy Maria-Pilar Prieto (Dr.) Kontakt administracyjny Ana Maria De La Fuente (Ms.) Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Koszt całkowity Brak danych Beneficjenci (1) Sortuj alfabetycznie Sortuj według wkładu UE Rozwiń wszystko Zwiń wszystko AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS Hiszpania Wkład UE € 600 000,00 Adres CALLE SERRANO 117 28006 Madrid Zobacz na mapie Region Comunidad de Madrid Comunidad de Madrid Madrid Rodzaj działalności Research Organisations Kierownik naukowy Maria-Pilar Prieto (Dr.) Kontakt administracyjny Ana Maria De La Fuente (Ms.) Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Koszt całkowity Brak danych