Cel The importance of carbon-based materials in biological applications has been recognized. Especially, nanodiamond particles (referred to as nanodiamonds, NDs) have started to emerge as novel candidate for promising applications in the field of nano-biotechnology as imaging probes and drug carriers. NDs do not show the toxicity of other nanoparticles, notably gold, making them ideal nanoscale drug delivery platforms. Furthermore, NDs can exhibit intrinsic fluorescence from point defects making them candidates for biomedical imaging applications. ND particles are particularly attractive for biomedical applications as functionalization and biomolecule immobilization are readily accomplished. Triggered drug release allows the functionalized NDs to find their targets before the drugs are activated by local conditions. In this sense, the NDs are performing the well established role of postdrugs, smuggeling the inactive compound to their targets where they are released through bond cleavage.The objective of the proposed program concerns the fabrication of NDs modified with photo-label linkers where different molecules can be directly attached, without chemically modification of the biomolecule itself. In a proof of principle, horse radish peroxidase (HRP) will be linked to NDs modified with the photo-label o-nitrobenzyl group and the release followed by UV/Vis. In a later state the controlled release of drugs such as ibuprofen, adriamycin or antigens will be looked at.The proposed research project brings together centers from France, the UK, Spain and the Ukrain. The network offers training in the fabrication and characterization of new materials for biological applications. Dziedzina nauki natural sciencesbiological sciencesbiochemistrybiomoleculesengineering and technologynanotechnologynano-materials Program(-y) FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Temat(-y) FP7-PEOPLE-2010-IRSES - Marie Curie Action "International Research Staff Exchange Scheme" Zaproszenie do składania wniosków FP7-PEOPLE-2010-IRSES Zobacz inne projekty w ramach tego zaproszenia System finansowania MC-IRSES - International research staff exchange scheme (IRSES) Koordynator UNIVERSITE DES SCIENCES ET TECHNOLOGIES DE LILLE - LILLE I Wkład UE € 66 500,00 Adres CITE SCIENTIFIQUE 59655 VILLENEUVE D'ASCQ Francja Zobacz na mapie Rodzaj działalności Higher or Secondary Education Establishments Kontakt administracyjny Sabine Szunerits (Prof.) Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Koszt całkowity Brak danych Uczestnicy (4) Sortuj alfabetycznie Sortuj według wkładu UE Rozwiń wszystko Zwiń wszystko UNIVERSITY OF BRIGHTON Zjednoczone Królestwo Wkład UE € 47 500,00 Adres LEWES ROAD MITHRAS HOUSE BN2 4AT Brighton Zobacz na mapie Region South East (England) Surrey, East and West Sussex Brighton and Hove Rodzaj działalności Higher or Secondary Education Establishments Kontakt administracyjny Peter Cragg (Dr.) Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Koszt całkowity Brak danych UNIVERSITE DE PICARDIE JULES VERNE Francja Wkład UE € 36 100,00 Adres CHEMIN DU THIL 80025 Amiens Zobacz na mapie Region Hauts-de-France Picardie Somme Rodzaj działalności Higher or Secondary Education Establishments Kontakt administracyjny Veaceslav Grosu (Mr.) Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Koszt całkowity Brak danych AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS Hiszpania Wkład UE € 20 900,00 Adres CALLE SERRANO 117 28006 Madrid Zobacz na mapie Region Comunidad de Madrid Comunidad de Madrid Madrid Rodzaj działalności Research Organisations Kontakt administracyjny Eusebio Jiménez Arroyo (Mr.) Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Koszt całkowity Brak danych UNIVERSIDAD DE SEVILLA Hiszpania Wkład UE € 15 200,00 Adres CALLE S. FERNANDO 4 41004 Sevilla Zobacz na mapie Region Sur Andalucía Sevilla Rodzaj działalności Higher or Secondary Education Establishments Kontakt administracyjny Margarita Martinez-Pais Loscertales (Ms.) Linki Kontakt z organizacją Opens in new window Strona internetowa Opens in new window Koszt całkowity Brak danych