Final Report Summary - LCS (Study of protein dynamics in living cells after DNA damage)
We declare a high quality of project realization. The goal of this project was to bring together biophysicists and biologists interested in protein kinetics and DNA damage responses. Suggested activities were guaranteed by the Institute of Biophysics Academy of Sciences of the Czech Republic and a group leader Eva Bartova, responsible for scientific goals, meeting organization and experimental strategies. All participants from Czech Republic, Russian Federation and Poland actively presented their work during their meetings and workshops, organized in the past 3 years. Many laboratory members (especially students) from the Institute in Novosibirsk and Brno started to be familiarized with possibilities of advanced microscopy techniques, including FRAP technique and FRAP analysis of protein kinetic in UV-induced DNA lesions. Research scientists and students from Novosibirsk's Institute contributed to this project by their biophysical approaches related to studies on protein kinetics. During the year 2013 we made an additional contract with Lomonosov Moscow State University in order to co-operate experimentally and organize a final meeting 2014 at this university. Our cooperation led to publication of 12 papers with acknowledgement to Marie Curie project. We published these papers in specialized scientific journals. Activities of whole scientific group are published and, for up-dated version, see: http://www.ibp.cz/cs/oddeleni/molekularni-cytologie-a-cytometrie/skupina-struktury-a-funkce-bunecneho-jadra/marie-curie-project-eu-pirses-ga-2010-269156-lcs