Final Report Summary - SELEFLU (Synthesis and Evaluation of 18F-Labelled N-F Reagents)
All these improvements can be used for radiosynthesis of [18F]trifluoromethylation of pharmaceutical candidates to facilitate drug development, especially for CNS diseases. Unprecedented 18F-PET tracers for clinical studies would be synthesized by using this methodology. Its operational simplicity allows for immediate use by most establishments providing they have access to basic PET chemistry infrastructure.