Objectif Activation of H2 is typically a domain of transition metal catalysis -even nature uses metal-centred reactions for this process. However, very recently Stephan and Erker have described metal free systems able to activate dihydrogen by the use of Frustrated Lewis Pairs (FLP), a combination of sterically hindered Lewis acids and Lewis bases that for this geometric reason are not able to quench each other. Moreover they were able to apply these systems for the reduction of some imines using H2 directly instead of any organic surrogate.Although this process is quite interesting, its applicability is nevertheless quite limited. Only silylenol ethers and very bulky imines can be satisfactorily reduced, non-encumbered ones simply react directly with B(C6F5)3, the ubiquitous Lewis acid used to form FLPs. To circumvent this obvious drawback I propose a new approach consisting in the use of completely organic molecules such as electron-poor allenes, alkenes, iminium salts and ketones as attractive alternatives to B(C6F5)3. The development of a totally organic FLP able to activate H2 reversibly goes far beyond the state-of-the-art as it is expected to allow the reduction of carbon-carbon and carbon-heteroatom double bonds without the use of any metal and employing directly H2. This wide-ranging extension of the FLP reactivity will clearly surpass classical metal catalysis in environmental issues as no noble metal will be necessary. Also, organocatalytic reductions will be outstripped in atom economy criteria as H2 and no heavier surrogate will be used as reducing agent. Champ scientifique natural scienceschemical sciencesorganic chemistryketonesnatural scienceschemical sciencescatalysis Programme(s) FP7-IDEAS-ERC - Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Thème(s) ERC-SG-PE5 - ERC Starting Grant - Materials and Synthesis Appel à propositions ERC-2011-StG_20101014 Voir d’autres projets de cet appel Régime de financement ERC-SG - ERC Starting Grant Institution d’accueil GEORG-AUGUST-UNIVERSITAT GOTTINGEN STIFTUNG OFFENTLICHEN RECHTS Contribution de l’UE € 485 447,30 Adresse WILHELMSPLATZ 1 37073 Gottingen Allemagne Voir sur la carte Région Niedersachsen Braunschweig Göttingen Type d’activité Higher or Secondary Education Establishments Chercheur principal Manuel Alcarazo Velasco (Prof.) Contact administratif Nadja Daghbouche (Ms.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée Bénéficiaires (2) Trier par ordre alphabétique Trier par contribution de l’UE Tout développer Tout réduire GEORG-AUGUST-UNIVERSITAT GOTTINGEN STIFTUNG OFFENTLICHEN RECHTS Allemagne Contribution de l’UE € 485 447,30 Adresse WILHELMSPLATZ 1 37073 Gottingen Voir sur la carte Région Niedersachsen Braunschweig Göttingen Type d’activité Higher or Secondary Education Establishments Chercheur principal Manuel Alcarazo Velasco (Prof.) Contact administratif Nadja Daghbouche (Ms.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée MAX PLANCK INSTITUT FUER KOHLENFORSCHUNG Participation terminée Allemagne Contribution de l’UE € 1 013 552,70 Adresse KAISER WILHELM PLATZ 1 45470 Muelheim An Der Ruhr Voir sur la carte Région Nordrhein-Westfalen Düsseldorf Mülheim an der Ruhr Type d’activité Research Organisations Contact administratif Salome Marenya (Ms.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée