Final Report Summary - K9GENES (Mapping canine genes and pathways to leverage personalized treatment options)
For this project, we have focused on collecting samples and performing association studies for different diseases as well as behavior. We have analyzed (or are in the process of analyzing) mammary tumors, osteosarcoma, atopic dermatitis, thyroiditis as well as behavior for at least three breeds per disease. We have found novel regions/genes associated in disease and have been following up the functional consequences of candidate mutations. In the long term, these biological discoveries could help understand and potentially test for and treat these diseases.