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CHEMometric and High-throughput Omics Analytical Methods for Assessment of Global Change Effects on Environmental and Biological Systems

Cel

We propose to develop new chemometric and high-throughput analytical methods to assess the effects of environmental and climate changes on target biological systems which are representative of ecosystems. This project will combine powerful chemometric and analytical high-throughput methodologies with toxicological tests to examine the effects of environmental stressors (like chemical pollution) and of climate change (like temperature, water scarcity or food shortage), on genomic and metabonomic profiles of target biological systems. The complex nature of experimental data produced by high-throughput analytical techniques, such as DNA microarrays, hyphenated chromatography-mass spectrometry or multi-dimensional nuclear magnetic resonance spectroscopy, requires powerful data analysis tools to extract, summarize and interpret the large amount of information that such megavariate data sets may contain. There is a need to improve and automate every step in the analysis of the data generated from genomic and metabonomic studies using new chemometric and multi- and megavariate tools. The main purpose of this project is to develop such tools. As a result of the whole study, a detailed report on the effects of global change and chemical pollution on the genomic and metabonomic profiles of a selected set of representative target biological systems will be delivered and used for global risk assessment. The information acquired, data sets and computer software will be stored in public data bases using modern data compression and data management technologies. And all the methodologies developed in the project will be published.

Zaproszenie do składania wniosków

ERC-2012-ADG_20120216
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System finansowania

ERC-AG - ERC Advanced Grant

Instytucja przyjmująca

AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
Wkład UE
€ 2 175 212,58
Adres
CALLE SERRANO 117
28006 Madrid
Hiszpania

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Region
Comunidad de Madrid Comunidad de Madrid Madrid
Rodzaj działalności
Research Organisations
Kontakt administracyjny
Guillermo Sanjuanbenito (Mr.)
Kierownik naukowy
Roman Tauler Ferrer (Prof.)
Linki
Koszt całkowity
Brak danych

Beneficjenci (2)