Objective Vision gives us enormous adaptive advantage because it allows us to see and react to events before they reach us. This predictive advantage is most obvious for an object in motion where the current trajectory predicts future location. It is equally important when the object’s motion results from the movement of our own eyes. Here our visual system uses knowledge about the upcoming motion of the eyes to predict the future location of the object. In this proposal, we will analyze both instances as two sides of a common predictive process that operates on the maps that control eye movements and spatial attention. We propose that this predictive positioning is involved not only in the guidance of eye movements and the deployment of attention to expected target locations but also for the location at which the target is perceived, including when a target is seen at a predicted location even though it is never there. This framework of a “master map” of target locations for perception as well as overt and covert orienting is a radical departure from the standard “labeled-line” model in which active neurons throughout the visual system specify the position of a target by virtue of their receptive field locations. The predictive shifts of location for moving stimuli and moving eyes, often deviating far from the retinal input, provide a powerful means for evaluating this proposal on many fronts. We will test these predictions with behavioral, fMRI and TMS techniques in healthy and neurological patients, and neurophysiological techniques in non-human primates. According to our working hypothesis, predictive position coding is a core function of the eye movement control system and its companion spatial attention system. The results of the proposed experiments will have the potential to show that it is the properties of action that determine the perception of position, reversing the common assumption that perception guides action. Fields of science natural sciencesbiological scienceszoologymammalogyprimatologyengineering and technologyelectrical engineering, electronic engineering, information engineeringelectronic engineeringcontrol systems Programme(s) FP7-IDEAS-ERC - Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Topic(s) ERC-AG-SH4 - ERC Advanced Grant - The Human Mind and its complexity Call for proposal ERC-2012-ADG_20120411 See other projects for this call Funding Scheme ERC-AG - ERC Advanced Grant Host institution Université Paris Descartes EU contribution € 1 768 365,32 Address Rue de l'Ecole de Médecine 75270 cedex 06 Paris France See on map Activity type Higher or Secondary Education Establishments Administrative Contact Lucie Guilloteau (Mrs.) Principal investigator Patrick Cavanagh (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data Beneficiaries (2) Sort alphabetically Sort by EU Contribution Expand all Collapse all Université Paris Descartes France EU contribution € 1 768 365,32 Address Rue de l'Ecole de Médecine 75270 cedex 06 Paris See on map Activity type Higher or Secondary Education Establishments Administrative Contact Lucie Guilloteau (Mrs.) Principal investigator Patrick Cavanagh (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE France EU contribution € 219 794,68 Address RUE DE TOLBIAC 101 75654 Paris See on map Region Ile-de-France Ile-de-France Paris Activity type Research Organisations Administrative Contact Isabelle Verdier (Mrs.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data