Objective Allogeneic stem cell transplantation (HSCT) is a life saving therapy for haematological disorders (leukaemia and lymphoma, inherited immune disorders, and aplastic anaemia). Over 7000 such transplants are carried out each year in Europe. However the over all survival rate after HSCT is poor (40-60%), and cure of patients is hampered by clinical complications that arise post-transplant; largely due to genetic and biological differences which exist between a given patient and donor. These differences includ e transplantation antigens (major and minor histocompatibility antigens). Pioneering research by Partners, have indicated that a number of non-HLA gene polymorphisms also affect the severity and incidence of transplant related complications. There is an urgent need to improve patient-donor matching at both the biological and genomic level which would develop HSCT beyond the current state of the art. HSCT outcomes will be improved if predictive assays, diagnostic tools and new therapeutics were developed and ultimately used by HSCT clinicians for individual patient based medicine. TRANS-NET teams have expertise in predictive bioassays, genomics, diagnostics and novel therapeutics who will train researchers in the key technologies of, mRNA expression profi ling, pathology, non-HLA immunogenetics and mechanisms of immune recognition; with the ultimate aim of applying the results of TRANS-NET in the HSCT clinical setting. TRANS-NET aims to 1) Define new biological/genomic indicators and novel therapies for th e potential development of new clinical strategies for improving the outcome and quality of life of HSCT patients. 2) Develop unique training programmes in genomics and immunobiology of transplantation and generate highly trained scientists with the abili ty to manage complex projects and understand the scientific challenges of individualised patient medicine. 3) Disseminate knowledge gained throughout the ERA and clinical HSCT centres across the EC. Fields of science natural sciencesbiological sciencesgeneticsmedical and health sciencesbasic medicineimmunologymedical and health sciencesmedical biotechnologycells technologiesstem cellsmedical and health sciencesclinical medicinetransplantationmedical and health sciencesclinical medicineoncologyleukemia Keywords Haematopoletic Haematopoletic stem cell transplantation Haematopoletic stem cell transplantation predicitive and preventative medicine predicitive and preventative medicine stem cell transplantation Programme(s) FP6-MOBILITY - Human resources and Mobility in the specific programme for research, technological development and demonstration "Structuring the European Research Area" under the Sixth Framework Programme 2002-2006 Topic(s) MOBILITY-1.1 - Marie Curie Research Training Networks (RTN) Call for proposal FP6-2002-MOBILITY-1 See other projects for this call Funding Scheme EIF - Marie Curie actions-Intra-European Fellowships Coordinator UNIVERSITY OF NEWCASTLE-UPON-TYNE EU contribution No data Address 6 KENSINGTON TERRACE NEWCASTLE-UPON-TYNE United Kingdom See on map Links Website Opens in new window Total cost No data Participants (12) Sort alphabetically Sort by EU Contribution Expand all Collapse all "BEREICH HUMANMEDIZIN" GEORG-AUGUST-UNIVERSITY GOETTINGEN Germany EU contribution No data Address Robert-Koch-Strasse 40 GOETTINGEN See on map Links Website Opens in new window Total cost No data CHARLES UNIVERSITY PRAGUE Czechia EU contribution No data Address Ovocný trh 5 PRAHA 1 See on map Links Website Opens in new window Total cost No data GSF - FORSCHUNGSZENTRUM FüR UMWELT UND GESUNDHHEIT, GMBH Germany EU contribution No data Address Ingolstaedter Landstrasse 1 NEUHERBERG See on map Links Website Opens in new window Total cost No data HEINRICH-HEINE-UNIVERSITäT DüSSELDORF Germany EU contribution No data Address Universitätstrasse 1 DUSSELDORF See on map Links Website Opens in new window Total cost No data HLA ET MEDECINE France EU contribution No data Address Rue de l'Ecole de Medecine, 15 PARIS See on map Total cost No data KLINIKUM DER UNIVERSITäT REGENSBURG Germany EU contribution No data Address Franz-Josef-Strauss-Strasse-Allee 11 REGENSBURG See on map Links Website Opens in new window Total cost No data MEDICAL UNIVERSITY OF VIENNA Austria EU contribution No data Address Spitalgasse 23 VIENNA See on map Links Website Opens in new window Total cost No data TECHNISCHE UNIVERSITAET MUENCHEN - KLINIKUM RECHTS DER ISAR Germany EU contribution No data Address ISMANNINGER STR. 22 MUNICH See on map Links Website Opens in new window Total cost No data THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN (HERINAFTER CALLED TCD) Ireland EU contribution No data Address College Green 2 DUBLIN See on map Links Website Opens in new window Total cost No data UNIVERSITETET I OSLO Norway EU contribution No data Address Problemveien 7 OSLO See on map Links Website Opens in new window Total cost No data UNIVERSITY OF GENEVA Switzerland EU contribution No data Address 24 rue du General Dufour GENEVA See on map Links Website Opens in new window Total cost No data UNIVERSITY OF GLASGOW United Kingdom EU contribution No data Address University Avenue GLASGOW See on map Links Website Opens in new window Total cost No data