Ziel
The STREP proposed here deals with biomimetics at the supramolecular or subcellular level which covers the nano- and microregime. In this regime, biological systems exhibit many active processes which are driven by a variety of biomolecular nanomaschines o r motors. The biomimetic systems studied in this STREP contain two types of linear motors, growing filaments and stepping motor proteins. Growing filaments generate pushing forces, stepping motor proteins exert pulling forces. The project has several scien tific objectives: to understand the molecular processes which are responsible for the generation of these forces; to elucidate the cooperative behavior of small and large groups of motor molecules which lead to active surface layers and active filament ass emblies or scaffolds; and to control and optimize the properties of these biomimetic systems. The research performed in this STREP is at the cutting edge of science and has a high potential for long-term innovation. Indeed, there are many possible applicat ions in bioengineering, pharmocology, and medicine such as sorting devices for biomolecules and biocolloids, active drug delivery systems, and force generating components for the development of nanoscale manufacturing.
Wissenschaftliches Gebiet
Schlüsselbegriffe
Thema/Themen
Aufforderung zur Vorschlagseinreichung
FP6-2003-NMP-TI-3-MAIN
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