Objective "Early detection of an incipient wound infection is a challenge for the attending physician , since its early diagnosis allows the timely initiation of treatment, thus reducing the severity of the disease . Currently, however, wound infection is not diagnosed until becoming already evident. As a consequence, the treatment of the patient is further complicated and more likely to have a negative outcome4. Often wounds are treated with antibiotics before even the infection appears, leading to overdoses and development of bacterial resistance to antibiotics.Considering that optimal efficiency is reached when a material serves multiple functions without compromise, consortium partners have discovered the means to convert wound dressings into a diagnostic tool capable to inform both patient and therapist about the wound status, thus directing towards the following therapeutic step. The proposed functional materials include a real time diagnostic reaction that positively influences the wound healing due to the timely intervention to treat infection or proteolytic stasis in the woundThe novel InFact technology will be translated into a low-cost, real-time diagnostic tool as a constituent part of a wound dressing material, i.e. the ""triple-P"" materials concept:- Protective - by a decoy substrate for destructive proteases- Predictive – providing a cumulative wound status signal to predict the infection transition- Proactive - changing the dressing according to a signal, rather than on a schedule base, will provide therapeutic response in time, and not too late.More specifically, the functional materials (e.g. absorbent fibres and hydrocolloid pads) will incorporate immobilized substrates for three enzymes: myeloperoxidase, lysozyme and elastase. Upon infection, these enzymatic activities are highly elevated in wound fluids, and can be detected by the color change of the functional materials, visible via a window in the dressing." Fields of science engineering and technologymaterials engineeringcolorsmedical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsantibioticsnatural sciencesbiological sciencesbiochemistrybiomoleculesproteinsenzymes Programme(s) FP7-NMP - Specific Programme "Cooperation": Nanosciences, Nanotechnologies, Materials and new Production Technologies Topic(s) NMP.2013.4.0-3 - From research to innovation: substantial steps forward in the industrial use of European intellectual assets, stimulating the use of newly developed materials and materials technologies by the industry Call for proposal FP7-NMP-2013-SME-7 See other projects for this call Funding Scheme CP-TP - Collaborative Project targeted to a special group (such as SMEs) Coordinator UNIVERSITAET FUER BODENKULTUR WIEN EU contribution € 661 811,00 Address GREGOR MENDEL STRASSE 33 1180 Wien Austria See on map Region Ostösterreich Wien Wien Activity type Higher or Secondary Education Establishments Administrative Contact Georg Guebitz (Prof.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data Participants (10) Sort alphabetically Sort by EU Contribution Expand all Collapse all STICHTING MEDISCH SPECTRUM TWENTE Netherlands EU contribution € 293 125,00 Address HAAKSBERGERSTRAAT 55 7513 ER Enschede See on map Region Oost-Nederland Overijssel Twente Activity type Other Administrative Contact Job Van Der Palen (Prof.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data DI DR ANDREAS PAAR KG Austria EU contribution € 381 980,00 Address LEECHGASSE 55/8 8010 GRAZ See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Andreas Paar (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data BAR ILAN UNIVERSITY Israel EU contribution € 392 320,00 Address BAR ILAN UNIVERSITY CAMPUS 52900 Ramat Gan See on map Activity type Higher or Secondary Education Establishments Administrative Contact Estelle Waise (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data DAVO STAR IMPEX SRL Romania EU contribution € 307 760,00 Address STR VALEA OTULUI 77-79 SECTOR 6 PARTER S1 S2 ETAJ 1 S3 061977 Bucuresti See on map Region Macroregiunea Trei Bucureşti-Ilfov Bucureşti Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Daniela Anton (Mrs.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data UNIVERSITAT POLITECNICA DE CATALUNYA Spain EU contribution € 464 231,00 Address CALLE JORDI GIRONA 31 08034 Barcelona See on map Region Este Cataluña Barcelona Activity type Higher or Secondary Education Establishments Administrative Contact Mercedes Torrellas (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data ASSOCIACAO UNIVERSIDADE EMPRESA PARA DESENVOLVIMENTO TECMINHO Portugal EU contribution € 344 760,00 Address CAMPUS DE AZUREM UNIVERSIDADE DO MINHO 4800 058 Guimaraes See on map Region Continente Norte Ave Activity type Other Administrative Contact Fernando Ribeiro (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data SYNOVO GMBH Germany EU contribution € 489 480,00 Address Paul Ehrlich Str 15 72076 Tuebingen See on map Region Baden-Württemberg Tübingen Tübingen, Landkreis Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Michael Burnet (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data CONVATEC LIMITED United Kingdom EU contribution € 497 380,00 Address GDC FIRST AVENUE - DEESIDE INDUSTRIAL PARK CH5 2NU DEESIDE FLINTSHIRE See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Philip Bowler (Mr.) Links Contact the organisation Opens in new window Total cost No data NEDERLANDSE ORGANISATIE VOOR TOEGEPAST NATUURWETENSCHAPPELIJK ONDERZOEK TNO Netherlands EU contribution € 306 046,00 Address ANNA VAN BUERENPLEIN 1 2595 DA Den Haag See on map Region West-Nederland Zuid-Holland Agglomeratie ’s-Gravenhage Activity type Research Organisations Administrative Contact Herman Lenting (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data OSM-DAN LTD Israel EU contribution € 199 080,00 Address 19 PRO NEEMAN YUVAL ST 7608665 Rehovot See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Pnina Dan (Dr.) Links Contact the organisation Opens in new window Total cost No data