Multifunctional micro- and nanostructures assembled from nanoscale metal-organic frameworks and inorganic nanoparticles

Cel

In InanoMOF, we aim to develop frontier Supramolecular and Nanochemistry methodologies for the synthesis of a novel class of structures via controlled assembly of nanoscale metal-organic frameworks (nanoMOFs) and inorganic nanoparticles (INPs). These methods will embody the premise that “controlled object-by-object nano-assembly is a ground-breaking approach to explore for producing systems of higher complexity with advanced functions”. The resulting hybrid nanoMOF@INPs will marry the unique properties of INPs (magnetism of iron oxide NPs and optics of Au NPs) to the functional porosity of MOFs.

The first part of InanoMOF encompasses the design, synthesis-assembly and characterisation of nanoMOF@INPs - advanced MOF-based sorbents that incorporate the functionality of the INPs used: magnetically controlled movement, in vivo detectability, enhanced biocompatibility and porosity, pollutant removal, or controlled sorption/delivery. The second part of InanoMOF entails studying the physicochemical properties of the synthesised nanoMOF@INPs and ascertaining their utility as drug-delivery/theranostic systems and as magnetic sorbents for pollutant removal. Specifically, we will study their stability in working media and determine their capacities for drug or pollutant sorption/delivery capacities. As proof-of-concept, we will study their toxicity in vitro and in vivo; enhancement of their in vitro therapeutic efficacy; and their capacity to remove pollutants (in real water and gasoline/diesel fuel samples) via magnetic assistance.

In InanoMOF we will endeavour to establish the synthetic bases for controlling the spatial ordering of nanoMOF crystals, whether alone or combined with other nanomaterials (e.g. INPs, graphene, etc.). We are confident that our work will ultimately enable researchers to create MOF-based composites having cooperative and synergistic properties and functions for myriad applications (e.g. heterogeneous catalysis, sensing and separation).

Dziedzina nauki

System finansowania

ERC-CG - ERC Consolidator Grants

Instytucja przyjmująca

FUNDACIO INSTITUT CATALA DE NANOCIENCIA I NANOTECNOLOGIA

Wkład UE

€ 1 942 664,98

Adres

CAMPUS DE LA UAB EDIFICI Q ICN2
08193 Cerdanyola Del Valles
Hiszpania

Region

Este Cataluña Barcelona

Rodzaj działalności

Research Organisations

Kierownik naukowy

Daniel Maspoch Comamala (Prof.)

Kontakt administracyjny

Marta Gonzalez Gomez (Ms.)

Linki

Kontakt z organizacją Strona internetowa

Koszt całkowity

Brak danych

Beneficjenci (1)