Objective
Through ERC-funded research, Prof. Wuite developed the DN-X-PRO as a method and instrument that enables direct visualization of DNA-protein interactions in real-time, at the single-molecule level, at super-resolution, under conditions similar to the cellular environment. Using the DN-X-PRO, researchers can manipulate and measure mechanical and structural properties of DNA-protein complexes, while simultaneously localizing individual proteins on the DNA, with nanometer accuracy and super-resolution. To date, such studies can only be performed by separate application of two or three different instruments, in conditions that do not resemble the cellular environment, with lower resolution. This results in a strong proposition to biomolecular researcher labs worldwide, allowing conduct of a range of experiments that are very complicated or not possible to date.
The PREMADIX project will result in a clear valorization strategy — based on elemental business insights that permit estimation of commercial and financial feasibility and business modeling and planning. Besides, a sound intellectual property (IP) strategy will be defined. In parallel, the DN-X-PRO will be physically prepared for marketing, translating the current prototype into a robust and user-friendly design accompanied by product sheets, control and analysis software, and user manuals. Finally, the PREMADIX team will assemble a business team, and start discussions with potential strategic partners and financers. By doing so, at the end of PREMADIX, the team will have strong assets for market introduction.
Fields of science
Call for proposal
ERC-2013-PoC
See other projects for this call
Funding Scheme
CSA-SA(POC) - Supporting action (Proof of Concept)Host institution
1081 HV Amsterdam
Netherlands