Deliverables Documents, reports (8) Micro crystals of light sensitive proteins Growth of micro-crystals of light sensitive proteins suitable for serial femtosecond crystallography studies at X-FELs. Publish novel structural insights Frontier studies on time-resolved diffraction and WAXS studies of light-sensitive proteins at XFELS Publish time-resolved diffraction/WAXS Papers reporting results on protein structural dynamics Short pulsed facility Commissioning of a short-pulsed X-ray facility at MAXIV in Lund Mid-term Dissemination and exploitation plan Update a shared plan for dissemination and exploitation of results Final Dissemination and exploitation plan A shared plan for dissemination and exploitation of results Crystallization of light sensitive proteins Crystallization of large crystals of light sensitive proteins suitable for Laue diffraction WAXS software suite Develop software to analyze time-resolved WAXS data incorporating molecular dynamics simulations Websites, patent fillings, videos etc. (1) Website Information to the public and scientific and industrial community Demonstrators, pilots, prototypes (2) New tools for nano-crystallography Develop and market new tools for sample handling and sample preparation for XFEL sources Software packages for analysing X-ray diffraction Develop software for processing, merging and scaling X-ray diffraction data from thousands of images Other (1) International Final Conference International conference open to external participants on X-probe results Publications Peer reviewed articles (26) Growing Protein Crystals with Distinct Dimensions Using Automated Crystallization Coupled with <em>In Situ</em> Dynamic Light Scattering Author(s): Daniela Baitan, Robin Schubert, Arne Meyer, Karsten Dierks, Markus Perbandt, Christian Betzel Published in: Journal of Visualized Experiments, Issue 138, 2018, ISSN 1940-087X Publisher: MYJoVE Corporation DOI: 10.3791/57070 Structural basis for selective inhibition of antibacterial target MraY, a membrane-bound enzyme involved in peptidoglycan synthesis Author(s): Jenny Hering, Elin Dunevall, Margareta Ek, Gisela Brändén Published in: Drug Discovery Today, Issue 23/7, 2018, Page(s) 1426-1435, ISSN 1359-6446 Publisher: Elsevier BV DOI: 10.1016/j.drudis.2018.05.020 Engineered ferritin for lanthanide binding Author(s): Lorenzo Calisti, Matilde Cardoso Trabuco, Alberto Boffi, Claudia Testi, Linda Celeste Montemiglio, Amédée des Georges, Irene Benni, Andrea Ilari, Bartłomiej Taciak, Maciej Białasek, Tomasz Rygiel, Magdalena Król, Paola Baiocco, Alessandra Bonamore Published in: PLOS ONE, Issue 13/8, 2018, Page(s) e0201859, ISSN 1932-6203 Publisher: Public Library of Science DOI: 10.1371/journal.pone.0201859 Retinal isomerization in bacteriorhodopsin captured by a femtosecond x-ray laser Author(s): Przemyslaw Nogly, Tobias Weinert, Daniel James, Sergio Carbajo, Dmitry Ozerov, Antonia Furrer, Dardan Gashi, Veniamin Borin, Petr Skopintsev, Kathrin Jaeger, Karol Nass, Petra Båth, Robert Bosman, Jason Koglin, Matthew Seaberg, Thomas Lane, Demet Kekilli, Steffen Brünle, Tomoyuki Tanaka, Wenting Wu, Christopher Milne, Thomas White, Anton Barty, Uwe Weierstall, Valerie Panneels, Eriko Nango, So I Published in: Science, 2018, Page(s) eaat0094, ISSN 0036-8075 Publisher: American Association for the Advancement of Science DOI: 10.1126/science.aat0094 FemtoMAX – an X-ray beamline for structural dynamics at the short-pulse facility of MAX IV Author(s): Henrik Enquist, Andrius Jurgilaitis, Amelie Jarnac, Åsa U. J. Bengtsson, Matthias Burza, Francesca Curbis, Christian Disch, J. Carl Ekström, Maher Harb, Lennart Isaksson, Marija Kotur, David Kroon, Filip Lindau, Erik Mansten, Jesper Nygaard, Anna I. H. Persson, Van Thai Pham, Michael Rissi, Sara Thorin, Chien-Ming Tu, Erik Wallén, Xiaocui Wang, Sverker Werin, Jörgen Larsson Published in: Journal of Synchrotron Radiation, Issue 25/2, 2018, Page(s) 570-579, ISSN 1600-5775 Publisher: Wiley-Blackwell on behalf of the International Union of Crystallography DOI: 10.1107/S1600577517017660 Communication: Demonstration of a 20 ps X-ray switch based on a photoacoustic transducer Author(s): A. Jarnac, Xiaocui Wang, Å. U. J. Bengtsson, J. C. Ekström, H. Enquist, A. Jurgilaitis, D. Kroon, A. I. H. Persson, V.-T. Pham, C. M. Tu, J. Larsson Published in: Structural Dynamics, Issue 4/5, 2017, Page(s) 051102, ISSN 2329-7778 Publisher: AIP publishing DOI: 10.1063/1.4993730 Substrate-induced conformational change in cytochrome P450 OleP Author(s): Giacomo Parisi, Linda Celeste Montemiglio, Alessandro Giuffrè, Alberto Macone, Antonella Scaglione, Gabriele Cerutti, Cécile Exertier, Carmelinda Savino, Beatrice Vallone Published in: The FASEB Journal, Issue 33/2, 2019, Page(s) 1787-1800, ISSN 0892-6638 Publisher: Federation of American Societies for Experimental Biology DOI: 10.1096/fj.201800450RR Probing Transient Photoinduced Charge Transfer in Prussian Blue Analogues with Time-Resolved XANES and Optical Spectroscopy Author(s): Serhane Zerdane, Marco Cammarata, Lodovico Balducci, Roman Bertoni, Laure Catala, Sandra Mazerat, Talal Mallah, Martin N. Pedersen, Michael Wulff, Kosuke Nakagawa, Hiroko Tokoro, Shin-ichi Ohkoshi, Eric Collet Published in: European Journal of Inorganic Chemistry, Issue 2018/3-4, 2018, Page(s) 272-277, ISSN 1434-1948 Publisher: John Wiley & Sons Ltd. DOI: 10.1002/ejic.201700657 Dynamic multiple-scattering treatment of X-ray absorption: Parameterization of a new molecular dynamics force field for myoglobin Author(s): Giovanni Chillemi, Massimiliano Anselmi, Nico Sanna, Cristiano Padrin, Lodovico Balducci, Marco Cammarata, Elisabetta Pace, Majed Chergui, Maurizio Benfatto Published in: Structural Dynamics, Issue 5/5, 2018, Page(s) 054101, ISSN 2329-7778 Publisher: American Crystallographic Association, Inc. DOI: 10.1063/1.5031806 Serial femtosecond crystallography structure of cytochrome c oxidase at room temperature Author(s): Rebecka Andersson, Cecilia Safari, Robert Dods, Eriko Nango, Rie Tanaka, Ayumi Yamashita, Takanori Nakane, Kensuke Tono, Yasumasa Joti, Petra Båth, Elin Dunevall, Robert Bosman, Osamu Nureki, So Iwata, Richard Neutze, Gisela Brändén Published in: Scientific Reports, Issue 7/1, 2017, ISSN 2045-2322 Publisher: Nature Publishing Group DOI: 10.1038/s41598-017-04817-z Initial metal–metal bond breakage detected by fs X-ray scattering in the photolysis of Ru 3 (CO) 12 in cyclohexane at 400 nm Author(s): Q. Y. Kong, M. G. Laursen, K. Haldrup, K. S. Kjær, D. Khakhulin, E. Biasin, T. B. van Driel, M. Wulff, V. Kabanova, R. Vuilleumier, S. Bratos, M. M. Nielsen, K. J. Gaffney, T. C. Weng, M. H. J. Koch Published in: Photochemical & Photobiological Sciences, Issue 18/2, 2019, Page(s) 319-327, ISSN 1474-905X Publisher: Royal Society of Chemistry DOI: 10.1039/c8pp00420j Megahertz serial crystallography Author(s): Max O. Wiedorn, Dominik Oberthür, Richard Bean, Robin Schubert, Nadine Werner, Brian Abbey, Martin Aepfelbacher, Luigi Adriano, Aschkan Allahgholi, Nasser Al-Qudami, Jakob Andreasson, Steve Aplin, Salah Awel, Kartik Ayyer, Saša Bajt, Imrich Barák, Sadia Bari, Johan Bielecki, Sabine Botha, Djelloul Boukhelef, Wolfgang Brehm, Sandor Brockhauser, Igor Cheviakov, Matthew A. Coleman, Francisco Cruz- Published in: Nature Communications, Issue 9/1, 2018, ISSN 2041-1723 Publisher: Nature Publishing Group DOI: 10.1038/s41467-018-06156-7 Double-flow focused liquid injector for efficient serial femtosecond crystallography Author(s): Dominik Oberthuer, Juraj Knoška, Max O. Wiedorn, Kenneth R. Beyerlein, David A. Bushnell, Elena G. Kovaleva, Michael Heymann, Lars Gumprecht, Richard A. Kirian, Anton Barty, Valerio Mariani, Aleksandra Tolstikova, Luigi Adriano, Salah Awel, Miriam Barthelmess, Katerina Dörner, P. Lourdu Xavier, Oleksandr Yefanov, Daniel R. James, Garrett Nelson, Dingjie Wang, George Calvey, Yujie Chen, Andrea Sc Published in: Scientific Reports, Issue 7/1, 2017, ISSN 2045-2322 Publisher: Nature Publishing Group DOI: 10.1038/srep44628 Pink-beam serial crystallography Author(s): A. Meents, M. O. Wiedorn, V. Srajer, R. Henning, I. Sarrou, J. Bergtholdt, M. Barthelmess, P. Y. A. Reinke, D. Dierksmeyer, A. Tolstikova, S. Schaible, M. Messerschmidt, C. M. Ogata, D. J. Kissick, M. H. Taft, D. J. Manstein, J. Lieske, D. Oberthuer, R. F. Fischetti, H. N. Chapman Published in: Nature Communications, Issue 8/1, 2017, ISSN 2041-1723 Publisher: Nature Publishing Group DOI: 10.1038/s41467-017-01417-3 Recent developments in CrystFEL Author(s): Thomas A. White, Valerio Mariani, Wolfgang Brehm, Oleksandr Yefanov, Anton Barty, Kenneth R. Beyerlein, Fedor Chervinskii, Lorenzo Galli, Cornelius Gati, Takanori Nakane, Alexandra Tolstikova, Keitaro Yamashita, Chun Hong Yoon, Kay Diederichs, Henry N. Chapman Published in: Journal of Applied Crystallography, Issue 49/2, 2016, Page(s) 680-689, ISSN 1600-5767 Publisher: IUCr DOI: 10.1107/s1600576716004751 Excimer based fluorescent pyrene–ferritin conjugate for protein oligomerization studies and imaging in living cells Author(s): Irene Benni, Matilde Cardoso Trabuco, Enrico Di Stasio, Alessandro Arcovito, Alberto Boffi, Francesco Malatesta, Alessandra Bonamore, Simone De Panfilis, Valeria de Turris, Paola Baiocco Published in: RSC Advances, Issue 8/23, 2018, Page(s) 12815-12822, ISSN 2046-2069 Publisher: Royal Society of Chemistry DOI: 10.1039/c8ra00210j Probing bulky ligand entry in engineered archaeal ferritins Author(s): Lorenzo Calisti, Irene Benni, Matilde Cardoso Trabuco, Paola Baiocco, Barbara Ruzicka, Alberto Boffi, Elisabetta Falvo, Francesco Malatesta, Alessandra Bonamore Published in: Biochimica et Biophysica Acta (BBA) - General Subjects, Issue 1861/2, 2017, Page(s) 450-456, ISSN 0304-4165 Publisher: Elsevier BV DOI: 10.1016/j.bbagen.2016.10.007 Structural basis for selectivity and diversity in angiotensin II receptors Author(s): Haitao Zhang, Gye Won Han, Alexander Batyuk, Andrii Ishchenko, Kate L. White, Nilkanth Patel, Anastasiia Sadybekov, Beata Zamlynny, Michael T. Rudd, Kaspar Hollenstein, Alexandra Tolstikova, Thomas A. White, Mark S. Hunter, Uwe Weierstall, Wei Liu, Kerim Babaoglu, Eric L. Moore, Ryan D. Katz, Jennifer M. Shipman, Margarita Garcia-Calvo, Sujata Sharma, Payal Sheth, Stephen M. Soisson, Raymond C. St Published in: Nature, Issue 544/7650, 2017, Page(s) 327-332, ISSN 0028-0836 Publisher: Nature Publishing Group DOI: 10.1038/nature22035 Real-Time Observation of Protein Dense Liquid Cluster Evolution during Nucleation in Protein Crystallization Author(s): Robin Schubert, Arne Meyer, Daniela Baitan, Karsten Dierks, Markus Perbandt, Christian Betzel Published in: Crystal Growth & Design, Issue 17/3, 2017, Page(s) 954-958, ISSN 1528-7483 Publisher: American Chemical Society DOI: 10.1021/acs.cgd.6b01826 Proximal and distal control for ligand binding in neuroglobin: role of the CD loop and evidence for His64 gating Author(s): Cécile Exertier, Lisa Milazzo, Ida Freda, Linda Celeste Montemiglio, Antonella Scaglione, Gabriele Cerutti, Giacomo Parisi, Massimiliano Anselmi, Giulietta Smulevich, Carmelinda Savino, Beatrice Vallone Published in: Scientific Reports, Issue 9/1, 2019, ISSN 2045-2322 Publisher: Nature Publishing Group DOI: 10.1038/s41598-019-41780-3 Humanized archaeal ferritin as a tool for cell targeted delivery Author(s): de Turris V., Cardoso Trabuco M., Peruzzi G., Boffi A., Testi C., Vallone B., Montemiglio L.C., des Georges A., Calisti L., Benni I., Bonamore A. and Baiocco P. Published in: nanoscale, 2017, ISSN 2040-3364 Publisher: Royal Society of Chemistry DOI: 10.5281/zenodo.2527178 Probing bulky ligand entry in engineered archaeal ferritins Author(s): Calisti L., Benni I., Cardoso Trabuco M., Baiocco P., Ruzicka B., Boffi A., Falvo E., Malatesta F. and Bonamore A. Published in: Biochim Biophys Acta, 2017, ISSN 0304-4165 Publisher: Elsevier BV DOI: 10.5281/zenodo.2528583 Studies of electron diffusion in photo-excited Ni using time-resolved X-ray diffraction Author(s): A. I. H. Persson, A. Jarnac, Xiaocui Wang, H. Enquist, A. Jurgilaitis, J. Larsson Published in: Applied Physics Letters, Issue 109/20, 2016, Page(s) 203115, ISSN 0003-6951 Publisher: American Institute of Physics DOI: 10.1063/1.4967470 MraY–antibiotic complex reveals details of tunicamycin mode of action Author(s): Jonna K Hakulinen, Jenny Hering, Gisela Brändén, Hongming Chen, Arjan Snijder, Margareta Ek, Patrik Johansson Published in: Nature Chemical Biology, Issue 13/3, 2017, Page(s) 265-267, ISSN 1552-4450 Publisher: Nature Publishing Group DOI: 10.1038/nchembio.2270 The Two-Photon Reversible Reaction of the Bistable Jumping Spider Rhodopsin-1 Author(s): David Ehrenberg, Niranjan Varma, Xavier Deupi, Mitsumasa Koyanagi, Akihisa Terakita, Gebhard F.X. Schertler, Joachim Heberle, Elena Lesca Published in: Biophysical Journal, Issue 116/7, 2019, Page(s) 1248-1258, ISSN 0006-3495 Publisher: Biophysical Society DOI: 10.1016/j.bpj.2019.02.025 Generation of a large compressive strain wave in graphite by ultrashort-pulse laser irradiation Author(s): Xiaocui Wang, A. Jarnac, J. C. Ekström, Å. U. J. Bengtsson, F. Dorchies, H. Enquist, A. Jurgilaitis, M. N. Pedersen, C.-M. Tu, M. Wulff, J. Larsson Published in: Structural Dynamics, Issue 6/2, 2019, Page(s) 024501, ISSN 2329-7778 Publisher: amarican crystallographic association DOI: 10.1063/1.5089291 Searching for OpenAIRE data... There was an error trying to search data from OpenAIRE No results available
