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Nanomethods to understand what makes an endogenous protein immunogenic

Publikacje

Interaction of fibrinogen–magnetic nanoparticle bioconjugates with integrin reconstituted into artificial membranes

Autorzy: Ulrike Martens, Una Janke, Sophie Möller, Delphine Talbot, Ali Abou-Hassan, Mihaela Delcea
Opublikowane w: Nanoscale, Numer 12/38, 2020, Strona(/y) 19918-19930, ISSN 2040-3364
Wydawca: Royal Society of Chemistry
DOI: 10.1039/d0nr04181e

Specific domain V reduction of beta-2-glycoprotein I induces protein flexibility and alters pathogenic antibody binding

Autorzy: Ina Buchholz, Thomas McDonnell, Peter Nestler, Sudarat Tharad, Martin Kulke, Anna Radziszewska, Vera M. Ripoll, Frank Schmidt, Elke Hammer, Jose L. Toca-Herrera, Anisur Rahman, Mihaela Delcea
Opublikowane w: Scientific Reports, Numer 11/1, 2021, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/s41598-021-84021-2

Lysine residues control the conformational dynamics of beta 2-glycoprotein I

Autorzy: Ina Buchholz, Peter Nestler, Susan Köppen, Mihaela Delcea
Opublikowane w: Physical Chemistry Chemical Physics, Numer 20/42, 2018, Strona(/y) 26819-26829, ISSN 1463-9076
Wydawca: Royal Society of Chemistry
DOI: 10.1039/c8cp03234c

Rupture Forces among Human Blood Platelets at different Degrees of Activation

Autorzy: Thi-Huong Nguyen, Raghavendra Palankar, Van-Chien Bui, Nikolay Medvedev, Andreas Greinacher, Mihaela Delcea
Opublikowane w: Scientific Reports, Numer 6, 2016, Strona(/y) 25402, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/srep25402

Anti-platelet factor 4/polyanion antibodies mediate a new mechanism of autoimmunity

Autorzy: Thi-Huong Nguyen, Nikolay Medvedev, Mihaela Delcea, Andreas Greinacher
Opublikowane w: Nature Communications, Numer 8, 2017, Strona(/y) 14945, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/ncomms14945

Biophysical tools to assess the interaction of PF4 with polyanions

Autorzy: M. Delcea, A. Greinacher
Opublikowane w: Thrombosis and Haemostasis, Numer 116/5, 2016, ISSN 0340-6245
Wydawca: Schattauer
DOI: 10.1160/TH16-04-0258

The impact of physiological stress conditions on protein structure and trypsin inhibition of serine protease inhibitor Kazal type 1 (SPINK1) and its N34S variant

Autorzy: Ina Buchholz, Felix Nagel, Annelie Klein, Preshit R. Wagh, Ujjwal M. Mahajan, Andreas Greinacher, Markus M. Lerch, Julia Mayerle, Mihaela Delcea
Opublikowane w: Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2019, Strona(/y) 140281, ISSN 1570-9639
Wydawca: Elsevier BV
DOI: 10.1016/j.bbapap.2019.140281

Drug-induced activation of integrin alpha IIb beta 3 leads to minor localized structural changes

Autorzy: Una Janke, Martin Kulke, Ina Buchholz, Norman Geist, Walter Langel, Mihaela Delcea
Opublikowane w: PLOS ONE, Numer 14/4, 2019, Strona(/y) e0214969, ISSN 1932-6203
Wydawca: Public Library of Science
DOI: 10.1371/journal.pone.0214969

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