The design and development of efficient biocatalytic cascades and biosynthetic pathways for the sustainable production of amines

Publikacje

Generation of Oxidoreductases with Dual Alcohol Dehydrogenase and Amine Dehydrogenase Activity

Autorzy: Vasilis Tseliou, Don Schilder, Marcelo F. Masman, Tanja Knaus, Francesco G. Mutti
Opublikowane w: Chemistry – A European Journal, Numer Vol. 27, Numer 10, 2021, Strona(/y) in press, ISSN 0947-6539
Wydawca: John Wiley & Sons Ltd.
DOI: 10.1002/chem.202003140

Parallel Interconnected Kinetic Asymmetric Transformation (PIKAT) with an Immobilized ω-Transaminase in Neat Organic Solvent

Autorzy: Wesley Böhmer, Lucien Koenekoop, Timothée Simon, Francesco G. Mutti
Opublikowane w: Molecules, Numer 25/9, 2020, Strona(/y) 2140, ISSN 1420-3049
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules25092140

Kinetic Resolution of Racemic Primary Amines Using Geobacillus stearothermophilus Amine Dehydrogenase Variant

Autorzy: Vasilis Tseliou, Tanja Knaus, Jan Vilím, Marcelo F. Masman, Francesco G. Mutti
Opublikowane w: ChemCatChem, Numer 12/8, 2020, Strona(/y) 2184-2188, ISSN 1867-3880
Wydawca: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/cctc.201902085

Highly efficient production of chiral amines in batch and continuous flow by immobilized ω-transaminases on controlled porosity glass metal-ion affinity carrier

Autorzy: Wesley Böhmer, Tanja Knaus, Alexey Volkov, Thierry K. Slot, N. Raveendran Shiju, Karim Engelmark Cassimjee, Francesco G. Mutti
Opublikowane w: Journal of Biotechnology, Numer 291, 2019, Strona(/y) 52-60, ISSN 0168-1656
Wydawca: Elsevier BV
DOI: 10.1016/j.jbiotec.2018.12.001

Efficient synthesis of enantiopure amines from alcohols using resting E. coli cells and ammonia

Autorzy: Joseline A. Houwman, Tanja Knaus, Magda Costa, Francesco G. Mutti
Opublikowane w: Green Chemistry, Numer 21/14, 2019, Strona(/y) 3846-3857, ISSN 1463-9262
Wydawca: Royal Society of Chemistry
DOI: 10.1039/c9gc01059a

Generation of amine dehydrogenases with increased catalytic performance and substrate scope from ε-deaminating L-Lysine dehydrogenase

Autorzy: Vasilis Tseliou, Tanja Knaus, Marcelo F. Masman, Maria L. Corrado, Francesco G. Mutti
Opublikowane w: Nature Communications, Numer 10/1, 2019, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-019-11509-x

In vitro biocatalytic pathway design: orthogonal network for the quantitative and stereospecific amination of alcohols

Autorzy: Tanja Knaus, Luca Cariati, Marcelo F. Masman, Francesco G. Mutti
Opublikowane w: Organic & Biomolecular Chemistry, Numer 15/39, 2017, Strona(/y) 8313-8325, ISSN 1477-0520
Wydawca: Royal Society of Chemistry
DOI: 10.1039/C7OB01927K

Biocatalytic hydrogen-borrowing cascades

Autorzy: Tanja Knaus, Francesco G. Mutti
Opublikowane w: Chimica Oggi - Chemistry Today, Numer 6 times per year, 2017, Strona(/y) 34-37, ISSN 0392-839X
Wydawca: Teknoscienze s.r.l.

Hydrogen-Borrowing Alcohol Bioamination with Coimmobilized Dehydrogenases

Autorzy: Wesley Böhmer, Tanja Knaus, Francesco G. Mutti
Opublikowane w: ChemCatChem, Numer 10/4, 2018, Strona(/y) 731-735, ISSN 1867-3880
Wydawca: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/cctc.201701366

A Chimeric Styrene Monooxygenase with Increased Efficiency in Asymmetric Biocatalytic Epoxidation

Autorzy: Maria L. Corrado, Tanja Knaus, Francesco G. Mutti
Opublikowane w: ChemBioChem, Numer 19/7, 2018, Strona(/y) 679-686, ISSN 1439-4227
Wydawca: John Wiley & Sons Ltd.
DOI: 10.1002/cbic.201700653

Catalytic Promiscuity of Galactose Oxidase: A Mild Synthesis of Nitriles from Alcohols, Air, and Ammonia

Autorzy: Jan Vilím, Tanja Knaus, Francesco G. Mutti
Opublikowane w: Angewandte Chemie International Edition, Numer 57/43, 2018, Strona(/y) 14240-14244, ISSN 1433-7851
Wydawca: John Wiley & Sons Ltd.
DOI: 10.1002/anie.201809411

Conversion of alcohols to enantiopure amines through dual-enzyme hydrogen-borrowing cascades

Autorzy: F. G. Mutti, T. Knaus, N. S. Scrutton, M. Breuer, N. J. Turner
Opublikowane w: Science, Numer 349/6255, 2015, Strona(/y) 1525-1529, ISSN 0036-8075
Wydawca: American Association for the Advancement of Science
DOI: 10.1126/science.aac9283

Amine dehydrogenases: efficient biocatalysts for the reductive amination of carbonyl compounds

Autorzy: Tanja Knaus, Wesley B?hmer, Francesco G. Mutti
Opublikowane w: Green Chem., Numer 19/2, 2017, Strona(/y) 453-463, ISSN 1463-9262
Wydawca: Royal Society of Chemistry
DOI: 10.1039/C6GC01987K

Continuous Flow Bioamination of Ketones in Organic Solvents at Controlled Water Activity using Immobilized ω‐Transaminases

Autorzy: Wesley Böhmer, Alexey Volkov, Karim Engelmark Cassimjee, Francesco G. Mutti
Opublikowane w: Advanced Synthesis & Catalysis, Numer 362/9, 2020, Strona(/y) 1858-1867, ISSN 1615-4150
Wydawca: John Wiley & Sons Ltd.
DOI: 10.1002/adsc.201901274

Mechanistic Insight into the Catalytic Promiscuity of Amine Dehydrogenases: Asymmetric Synthesis of Secondary and Primary Amines

Autorzy: Vasilis Tseliou, Marcelo F. Masman, Wesley Böhmer, Tanja Knaus, Francesco G. Mutti
Opublikowane w: ChemBioChem, Numer 20/6, 2019, Strona(/y) 800-812, ISSN 1439-4227
Wydawca: John Wiley & Sons Ltd.
DOI: 10.1002/cbic.201800626

Regio- and stereoselective multi-enzymatic aminohydroxylation of β-methylstyrene using dioxygen, ammonia and formate

Autorzy: Maria L. Corrado, Tanja Knaus, Francesco G. Mutti
Opublikowane w: Green Chemistry, Numer 21/23, 2019, Strona(/y) 6246-6251, ISSN 1463-9262
Wydawca: Royal Society of Chemistry
DOI: 10.1039/c9gc03161h

Prawa własności intelektualnej

Redox self-sufficient biocatalytic amination of alcohols

Numer wniosku/publikacji: EP 14175632
Data: 2014-07-03

Redox self-sufficient biocatalytic amination of alcohols

Numer wniosku/publikacji: EP 14175632
Data: 2014-07-03
Wnioskodawca/wnioskodawcy: THE UNIVERSITY OF MANCHESTER

Redox self-sufficient biocatalytic amination of alcohols

Numer wniosku/publikacji: EP 14175632
Data: 2014-07-03

L-LYSINE EPSILON-DEHYDROGENASE VARIANTS AND USES THEREOF

Numer wniosku/publikacji: 20 20053918
Data: 2020-02-14

PROCESS FOR THE MANUFACTURE OF NITRILE COMPOUNDS

Numer wniosku/publikacji: 20 19069715
Data: 2019-07-22

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