Mechanisms of Gene Silencing by the Glucocorticoid Receptor

Project Information

SILENCE

Grant agreement ID: 638573

DOI 10.3030/638573

Project closed

EC signature date 27 April 2015

Start date 1 August 2015

End date 31 July 2021

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 496 275,00

EU contribution € 1 496 275,00

Coordinated by

HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH
Germany

Publications

Peer reviewed articles (8)

Cistromic Reprogramming of the Diurnal Glucocorticoid Hormone Response by High-Fat Diet

Author(s): Fabiana Quagliarini, Ashfaq Ali Mir, Kinga Balazs, Michael Wierer, Kenneth Allen Dyar, Celine Jouffe, Konstantinos Makris, Johann Hawe, Matthias Heinig, Fabian Volker Filipp, Grant Daniel Barish, Nina Henriette Uhlenhaut
Published in: Molecular Cell, Issue 76/4, 2019, Page(s) 531-545.e5, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2019.10.007

Seq-ing answers: Current data integration approaches to uncover mechanisms of transcriptional regulation

Author(s): Barbara Höllbacher, Kinga Balázs, Matthias Heinig, N. Henriette Uhlenhaut
Published in: Computational and Structural Biotechnology Journal, Issue 18, 2020, Page(s) 1330-1341, ISSN 2001-0370
Publisher: Elsevier BV
DOI: 10.1016/j.csbj.2020.05.018

Protocol for using heterologous spike-ins to normalize for technical variation in chromatin immunoprecipitation

Author(s): Franziska Greulich, Aikaterini Mechtidou, Teresa Horn, Nina Henriette Uhlenhaut
Published in: STAR Protocols, Issue 2/3, 2021, Page(s) 100609, ISSN 2666-1667
Publisher: Cell Press/Elsevier
DOI: 10.1016/j.xpro.2021.100609

DNA residence time is a regulatory factor of transcription repression

Author(s): Karen Clauß, Achim P. Popp, Lena Schulze, Johannes Hettich, Matthias Reisser, Laura Escoter Torres, N. Henriette Uhlenhaut, J. Christof M. Gebhardt
Published in: Nucleic Acids Research, Issue 45/19, 2017, Page(s) 11121-11130, ISSN 0305-1048
Publisher: Oxford University Press
DOI: 10.1093/nar/gkx728

There goes the neighborhood: Assembly of transcriptional complexes during the regulation of metabolism and inammation by the glucocorticoid receptor

Author(s): Franziska Greulich, M. Charlotte Hemmer, David A. Rollins, Inez Rogatsky, N. Henriette Uhlenhaut
Published in: Steroids, 2016, ISSN 0039-128X
Publisher: Elsevier BV
DOI: 10.1016/j.steroids.2016.05.003

Anti-inflammatory functions of the glucocorticoid receptor require DNA binding

Author(s): Laura Escoter-Torres, Franziska Greulich, Fabiana Quagliarini, Michael Wierer, Nina Henriette Uhlenhaut
Published in: Nucleic Acids Research, Issue 48/15, 2020, Page(s) 8393-8407, ISSN 0305-1048
Publisher: Oxford University Press
DOI: 10.1093/nar/gkaa565

Anti-inflammatory glucocorticoid action: genomic insights and emerging concepts

Author(s): Afzal Pasha Syed, Franziska Greulich, Suhail Akhtar Ansari, Nina Henriette Uhlenhaut
Published in: Current Opinion in Pharmacology, Issue 53, 2020, Page(s) 35-44, ISSN 1471-4892
Publisher: Elsevier BV
DOI: 10.1016/j.coph.2020.03.003

The glucocorticoid receptor recruits the COMPASS complex to regulate inflammatory transcription at macrophage enhancers

Author(s): Franziska Greulich, Michael Wierer, Aikaterini Mechtidou, Omar Gonzalez-Garcia, N. Henriette Uhlenhaut
Published in: Cell Reports, Issue 34/6, 2021, Page(s) 108742, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2021.108742