Rezultaty
Minute conference calls for coordination of visiting periods
D2.7The deliverable lead is the partner Temple University. Lecture notes on computational docking.
D1.7Lecture notes on high performance computing.
D6.1.4Minute conference calls for coordination of visiting periods
D6.1.1Minute conference calls for coordination of visiting periods
D6.1.7Minute conference calls for coordination of visiting periods
D6.1.6Minute conference calls for coordination of visiting periods
D6.3.1Submitted grant proposals to European Community, NSF and NIH (USA), etc.
D6.1.5Minute conference calls for coordination of visiting periods
D6.1.2Minute conference calls for coordination of visiting periods
Enabling technique for the decoration of DNA nanostructures with proteins.
D2.8The deliverable lead is the partner Temple University. Computational codes to analyse long MD trajectories.
D5.3Standardized protocols for the use of the immune-device for the study of GAA and autophagy associated proteins in cultured cells.
D4.2The deliverable lead is the partner CONICET. Feedback on the functions of large nanodecoders (5-30 fluorescent dyes) for detecting MAGE proteins in cells and histological tissue samples.
D5.2Feedback on the functions of large nanodecoders (5-30 fluorescent dyes) for detecting glycogenosis type II-related proteins in cells.
D1.8Computational codes to setup coarse-grain simulations.
D4.1The deliverable lead is the partner CONICET. Feedback on the functions of small nanodecoders (1-5 fluorescent dyes) for detecting MAGE proteins in cells and histological tissues samples.
D5.1Feedback on the functions of small nanodecoders (1-5 fluorescent dyes) for detecting glycogenosis type II-related proteins in cells.
D5.4Identification of possible therapeutic small molecules able to restore GAA expression and revert the pathological cellular phenotype.
D3.1Protocols and sequences for the synthesis of a universal DNA-protein linker for nanodecoders based on DNA nanoparticles.
D3.2Protocols and sequences for the synthesis of a universal DNA-protein linker for nanodecoders based on DNA origami.
Training of young researchers on cell culture-related techniques and advanced cells imaging.
D1.1Immuno-nanodecoders based on a single DNA probe functioning with hybridization reactions.
D6.4.1Seminars held at industries and SME.
D1.2Immuno-nanodecoders based on complex DNA nanostructure, comprising several DNA probes, and functioning with hybridization reactions.
D2.6The deliverable lead is the partner Temple University. Characterization of the molecular factors affecting catalytic efficiency of RNase H
D2.3The deliverable lead is the partner Temple University. Training young scientist on experimental methods for studying the behaviour of DNA:RNA nanostructures in solution.
D2.5The deliverable lead is the partner Temple University. Structure of the catalytically active complex between RNase H and the nanodecoder
D4.3The deliverable lead is the partner CONICET. Training and exchange-I for researches not involved in biomedical issues (by M.12). The availability of the device is scheduled for month 18, so the results obtained from task 4.1 and 4.2 are expected for months 24-30.
D2.2The deliverable lead is the partner Temple University. Immuno-nanodecoders based on complex DNA:RNA nanostructures, comprising several DNA probes, and functioning with DNA:RNA hybridization and RNase H enzymatic reactions.
D1.5Characterization of the global structural constraints to design nanodecoders.
D3.4Training junior researcher in sequence selective conjugation of protein-DNA nanostructures.
D1.6Characterization of the molecular factors affecting accessibility of the stem-loop to on- and off-code.
D2.4The deliverable lead is the partner Temple University. Training young scientist on experimental methods for studying the behaviour of DNA:RNA nanostructures on surfaces.
D1.4Training young scientist on experimental methods for studying the behaviour of DNA nanostructures on surfaces.
D2.1The deliverable lead is the partner Temple University. Immuno-nanodecoders based on a single DNA probe, and functioning with DNA:RNA hybridization and enzymatic reactions.
D4.4The deliverable lead is the partner CONICET. Training and exchange-II for researches involved in WP5.
D1.3Training young scientist on experimental methods for studying the behaviour of DNA nanostructures in solution.
Publikacje
Autorzy:
Wenwei Ma, Angela Saccardo, Danilo Roccatano, Dorothy Aboagye-Mensah, Mohammad Alkaseem, Matthew Jewkes, Francesca Di Nezza, Mark Baron, Mikhail Soloviev, Enrico Ferrari
Opublikowane w:
Nature Communications, Numer 9/1, 2018, ISSN 2041-1723
Wydawca:
Nature Publishing Group
DOI:
10.1038/s41467-018-03931-4
Autorzy:
W. Ma, D. Aboagye-Mensah, M. Soloviev, B. Davletov, E. Ferrari
Opublikowane w:
Materials Today: Proceedings, Numer 4/7, 2017, Strona(/y) 6923-6929, ISSN 2214-7853
Wydawca:
Elsevier
DOI:
10.1016/j.matpr.2017.07.021
Autorzy:
Anish Parmar, Abhishek Iyer, Stephen H. Prior, Daniel G. Lloyd, Eunice Tze Leng Goh, Charlotte S. Vincent, Timea Palmai-Pallag, Csanad Z. Bachrati, Eefjan Breukink, Annemieke Madder, Rajamani Lakshminarayanan, Edward J. Taylor, Ishwar Singh
Opublikowane w:
Chemical Science, Numer 8/12, 2017, Strona(/y) 8183-8192, ISSN 2041-6520
Wydawca:
Royal Society of Chemistry
DOI:
10.1039/c7sc03241b
Wyszukiwanie danych OpenAIRE...
Podczas wyszukiwania danych OpenAIRE wystąpił błąd
Brak wyników