Objective Small metal implants such as dental implants or bone-anchored hearing aids need very good mechanical properties and corrosion resistance to avoid local inflammation and remain integrated in bone. In GLASSIX, Ti-based metallic glasses will be developed specifically for small implants using a new approach to evaluate biocompatibility. This is usually tested on passive metal surfaces, but recent work has shown that mechanically-assisted crevice corrosion (MACC) can generate metal particles and corrosion products that damage the surrounding tissue. In situ characterisation of corrosion products with synchrotron X-rays will be used to design standard simulated corrosion products that will then be tested on human cells to evaluate which corrosion products are most damaging. The findings from this new approach will be fed back into the alloy development process together with information on feasibility of manufacture from Anthogyr, a leading manufacturer. The project combines the ER’s expertise in metallic glasses, and the expertise of host researchers in corrosion, X-ray methods, clinical and biomedical research, and will equip the ER to carry out cutting edge research in an academic environment that can readily be translated into clinical and commercial success in the biomedical devices sector. Fields of science medical and health sciencesclinical medicineodontologydental implantologyengineering and technologymaterials engineeringcoating and filmsengineering and technologynanotechnologynano-materialsengineering and technologyindustrial biotechnologybiomaterialsmedical and health sciencesmedical biotechnologyimplants Programme(s) H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility Topic(s) MSCA-IF-2014-EF - Marie Skłodowska-Curie Individual Fellowships (IF-EF) Call for proposal H2020-MSCA-IF-2014 See other projects for this call Funding Scheme MSCA-IF-EF-ST - Standard EF Coordinator THE UNIVERSITY OF BIRMINGHAM Net EU contribution € 195 454,80 Address Edgbaston B15 2TT Birmingham United Kingdom See on map Region West Midlands (England) West Midlands Birmingham Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 195 454,80