Integrating Genomics and Avatar Mouse Models to Personalize Pancreatic Cancer Treatment

Informazioni relative al progetto

AVATAR

ID dell’accordo di sovvenzione: 670582

DOI 10.3030/670582

Progetto concluso il 31 Gennaio 2020

Data della firma CE 25 Settembre 2015

Data di avvio 1 Ottobre 2015

Data di completamento 30 Settembre 2020

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale € 2 498 687,50

Contributo UE € 2 498 687,50

Coordinato da

HOSPITAL UNIVERSITARIO DE FUENLABRADA
Spain

Pubblicazioni

Conference proceedings (1)

Abstract CT119: Organoid sensitivity in pancreatic cancer correlates with clinical response to treatment and reveals utility for reducing toxicity: Preliminary results from the HOPE trial

Autori: Joseph Elan Grossman, Ling Huang, Lakshmi Muthuswamy, Sofia Perea, Dipikaa Akshinthala, Raul Gonzalez, Leo Tsai, Jonah Cohen, Mandeep Sawhney, Douglas Pleskow, Tyler M. Berzin, Bruno Bockorny, Andrea Bullock, Benjamin Schlechter, Mary Linton B. Peters, Catherine Conahan, Supraja Narasimhan, Christine Lim, Roger Davis, Robert Besaw, Martin Smith, Tara Kent, Mark Callery, Senthil K. Muthuswamy, Manu
Pubblicato in: Tumor Biology, 2020, Pagina/e CT119-CT119
Editore: American Association for Cancer Research
DOI: 10.1158/1538-7445.am2020-ct119

Peer reviewed articles (2)

Complete Regression of Advanced Pancreatic Ductal Adenocarcinomas upon Combined Inhibition of EGFR and C-RAF

Autori: María Teresa Blasco, Carolina Navas, Guillermo Martín-Serrano, Osvaldo Graña-Castro, Carmen G. Lechuga, Laura Martín-Díaz, Magdolna Djurec, Jing Li, Lucia Morales-Cacho, Laura Esteban-Burgos, Javier Perales-Patón, Emilie Bousquet-Mur, Eva Castellano, Harrys K.C. Jacob, Lavinia Cabras, Monica Musteanu, Matthias Drosten, Sagrario Ortega, Francisca Mulero, Bruno Sainz, Nelson Dusetti, Juan Iova
Pubblicato in: Cancer Cell, Numero 35/4, 2019, Pagina/e 573-587.e6, ISSN 1535-6108
Editore: Cell Press
DOI: 10.1016/j.ccell.2019.03.002

Interrogating open issues in cancer precision medicine with patient-derived xenografts

Autori: Annette T. Byrne, Denis G. Alférez, Frédéric Amant, Daniela Annibali, Joaquín Arribas, Andrew V. Biankin, Alejandra Bruna, Eva Budinská, Carlos Caldas, David K. Chang, Robert B. Clarke, Hans Clevers, George Coukos, Virginie Dangles-Marie, S. Gail Eckhardt, Eva Gonzalez-Suarez, Els Hermans, Manuel Hidalgo, Monika A. Jarzabek, Steven de Jong, Jos Jonkers, Kristel Kemper, Luisa Lanfrancone, Gunh
Pubblicato in: Nature Reviews Cancer, Numero 17/4, 2017, Pagina/e 254-268, ISSN 1474-175X
Editore: Nature Publishing Group
DOI: 10.1038/nrc.2016.140