Periodic Reporting for period 1 - PANOSTICS (The AA2-Ratio: A Novel Diagnostic Biomarker for Primary Aldosteronism)
Période du rapport: 2015-04-01 au 2015-08-31
PA is a severe, but curable form of treatment resistant hypertension. Treatment resistant hypertension affects more than 1 out of 50 Europeans and clinical guidelines recommend screening for PA among this high cardiovascular risk patient cohort. Unfortunately, adherence to these guidelines in clinical practice is poor, which is caused by the low diagnostic performance of currently available tests in patients on anti-hypertensive therapy and results in a high number of preventable cardiovascular events. The broad implementation of the AA2-Ratio into clinical practice would result in an improvement of the cure rate for PA and therefore prevent hypertension associated cardiovascular events, which are major cost drivers for health care systems in Europe.