Pubblicazioni Peer reviewed articles (21) MCT1 is a predictive marker for lenalidomide maintenance therapy in multiple myeloma Autori: Jacob Stroh, Anja Seckinger, Michael Heider, Martina Rudelius, Ruth Eichner, Markus Schick, Jolanta Slawska, Martina Emde-Rajaratnam, Hans Salwender, Uta Bertsch, Hartmut Goldschmidt, Katja Weisel, Christof Scheid, Ulrich Keller, Dirk Hose, Florian Bassermann Pubblicato in: Blood Advances, Issue 24739537, 2022, ISSN 2473-9537 Editore: Elsevier DOI: 10.1182/bloodadvances.2021005532 RIG-I activation is critical for responsiveness to checkpoint blockade Autori: Simon Heidegger, Alexander Wintges, Florian Stritzke, Sarah Bek, Katja Steiger, Paul-Albert Koenig, Sascha Göttert, Thomas Engleitner, Rupert Öllinger, Tatiana Nedelko, Julius C. Fischer, Vladimir Makarov, Christof Winter, Roland Rad, Marcel R.M. van den Brink, Jürgen Ruland, Florian Bassermann, Timothy A. Chan, Tobias Haas, Hendrik Poeck Pubblicato in: Science Immunology, Issue 4/39, 2019, Page(s) eaau8943, ISSN 2470-9468 Editore: Science Immunology DOI: 10.1126/sciimmunol.aau8943 Multiple Myeloma: Molecular Pathogenesis and Disease Evolution Autori: Michael Heider, Katharina Nickel, Marion Högner, Florian Bassermann Pubblicato in: Oncology Research and Treatment, Issue 22965270, 2021, ISSN 2296-5270 Editore: S. Karger AG DOI: 10.1159/000520312 SUMOylation inhibition overcomes proteasome inhibitor resistance in multiple myeloma Autori: Guus J J E Heynen, Francis Baumgartner, Michael Heider, Upayan Patra, Maximilian Holz, Jan Braune, Melanie Kaiser, Isabell Schäffer, Stefanos A Bamopoulos, Evelyn Ramberger, Arunima Murgai, Yuen Lam Dora Ng, Uta Margareta Demel, Dominik Laue, Sven Liebig, Josefine Krüger, Martin Janz, Axel Nogai, Markus Schick, Philipp Mertins, Stefan Müller, Florian Bassermann, Jan Krönke, Ulrich Keller, Matt Pubblicato in: Blood Advances, Issue 24739529, 2022, ISSN 2473-9529 Editore: Elsevier DOI: 10.1182/bloodadvances.2022007875 MCL-1 gains occur with high frequency in lung adenocarcinoma and can be targeted therapeutically Autori: Enkhtsetseg Munkhbaatar, Michelle Dietzen, Deepti Agrawal, Martina Anton, Moritz Jesinghaus, Melanie Boxberg, Nicole Pfarr, Pidassa Bidola, Sebastian Uhrig, Ulrike Höckendorf, Anna-Lena Meinhardt, Adam Wahida, Irina Heid, Rickmer Braren, Ritu Mishra, Arne Warth, Thomas Muley, Patrina S. P. Poh, Xin Wang, Stefan Fröhling, Katja Steiger, Julia Slotta-Huspenina, Martijn van Griensven, Franz Pfeiffe Pubblicato in: Nature Communications, Issue 11/1, 2020, ISSN 2041-1723 Editore: Nature Publishing Group DOI: 10.1038/s41467-020-18372-1 FBXO11-mediated proteolysis of BAHD1 relieves PRC2-dependent transcriptional repression in erythropoiesis Autori: Peng Xu, Daniel C. Scott, Beisi Xu, Yu Yao, Ruopeng Feng, Li Cheng, Kalin Mayberry, Yong-Dong Wang, Wenjian Bi, Lance E. Palmer, Moeko T. King, Hong Wang, Yuxin Li, Yiping Fan, Arno F. Alpi, Chunliang Li, Junmin Peng, James Papizan, Shondra M. Pruett-Miller, Ria Spallek, Florian Bassermann, Yong Cheng, Brenda A. Schulman, Mitchell J. Weiss Pubblicato in: Blood, Issue 137/2, 2021, Page(s) 155-167, ISSN 0006-4971 Editore: American Society of Hematology DOI: 10.1182/blood.2020007809 Antagonistic activities of CDC14B and CDK1 on USP9X regulate WT1-dependent mitotic transcription and survival Autori: Michael Dietachmayr, Abirami Rathakrishnan, Oleksandra Karpiuk, Felix von Zweydorf, Thomas Engleitner, Vanesa Fernández-Sáiz, Petra Schenk, Marius Ueffing, Roland Rad, Martin Eilers, Christian Johannes Gloeckner, Katharina Clemm von Hohenberg, Florian Bassermann Pubblicato in: Nature Communications, Issue 11/1, 2020, ISSN 2041-1723 Editore: Nature Publishing Group DOI: 10.1038/s41467-020-15059-5 The IMiD target CRBN determines HSP90 activity toward transmembrane proteins essential in multiple myeloma Autori: Michael Heider, Ruth Eichner, Jacob Stroh, Volker Morath, Anna Kuisl, Jana Zecha, Jannis Lawatscheck, Kheewoong Baek, Anne-Kathrin Garz, Martina Rudelius, Friedrich-Christian Deuschle, Ulrich Keller, Simone Lemeer, Mareike Verbeek, Katharina S. Götze, Arne Skerra, Wolfgang A. Weber, Johannes Buchner, Brenda A. Schulman, Bernhard Kuster, Vanesa Fernández-Sáiz, Florian Bassermann Pubblicato in: Molecular Cell, Issue 81/6, 2021, Page(s) 1170-1186.e10, ISSN 1097-2765 Editore: Cell Press DOI: 10.1016/j.molcel.2020.12.046 Linking post-translational modifications and protein turnover by site-resolved protein turnover profiling Autori: Jana Zecha, Wassim Gabriel, Ria Spallek, Yun-Chien Chang, Julia Mergner, Mathias Wilhelm, Florian Bassermann, Bernhard Kuster Pubblicato in: nature communications, Issue 20411723, 2022, ISSN 2041-1723 Editore: Nature Publishing Group DOI: 10.1038/s41467-021-27639-0 The OTUD6B-LIN28B-MYC axis determines the proliferative state in multiple myeloma Autori: Carmen Paulmann, Ria Spallek, Oleksandra Karpiuk, Michael Heider, Isabell Schäffer, Jana Zecha, Susan Klaeger, Michaela Walzik, Rupert Öllinger, Thomas Engleitner, Matthias Wirth , Ulrich Keller, Jan Krönke, Martina Rudelius, Susanne Kossatz, Roland Rad, Bernhard Kuster, Florian Bassermann Pubblicato in: The EMBO Journal, Issue 02614189, 2022, ISSN 0261-4189 Editore: Nature Publishing Group DOI: 10.15252/embj.2022110871 Tumor cell‐intrinsic RIG‐I signaling governs synergistic effects of immunogenic cancer therapies and checkpoint inhibitors in mice Autori: Hendrik Poeck, Alexander Wintges, Sarah Dahl, Florian Bassermann, Tobias Haas, Simon Heidegger Pubblicato in: European Journal of Immunology, 2018, ISSN 0014-2980 Editore: John Wiley & Sons Ltd. DOI: 10.1002/eji.202049158 Circulating Tumor DNA Profiling of a Diffuse Large B Cell Lymphoma Patient with Secondary Acute Myeloid Leukemia Autori: Irina A. Kerle; Ludwig Jägerhuber; Ramona Secci; Nicole Pfarr; Philipp Blüm; Romina Roesch; Katharina S. Götze; Wilko Weichert; Florian Bassermann; Jürgen Ruland; Christof Winter Pubblicato in: Cancers, Issue 20726694, 2022, ISSN 2072-6694 Editore: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/cancers14061371 The target landscape of clinical kinase drugs Autori: Susan Klaeger, Stephanie Heinzlmeir, Mathias Wilhelm, Harald Polzer, Binje Vick, Paul-Albert Koenig, Maria Reinecke, Benjamin Ruprecht, Svenja Petzoldt, Chen Meng, Jana Zecha, Katrin Reiter, Huichao Qiao, Dominic Helm, Heiner Koch, Melanie Schoof, Giulia Canevari, Elena Casale, Stefania Re Depaolini, Annette Feuchtinger, Zhixiang Wu, Tobias Schmidt, Lars Rueckert, Wilhelm Becker, Jan Huenges, Anne Pubblicato in: Science, Issue 358/6367, 2017, Page(s) eaan4368, ISSN 0036-8075 Editore: American Association for the Advancement of Science DOI: 10.1126/science.aan4368 IKZF1 expression is a prognostic marker in newly diagnosed standard-risk multiple myeloma treated with lenalidomide and intensive chemotherapy: a study of the German Myeloma Study Group (DSMM) Autori: J Krönke, F Kuchenbauer, M Kull, V Teleanu, L Bullinger, D Bunjes, A Greiner, S Kolmus, S Köpff, M Schreder, L-O Mügge, C Straka, M Engelhardt, H Döhner, H Einsele, F Bassermann, R Bargou, S Knop, C Langer Pubblicato in: Leukemia, Issue 31/6, 2017, Page(s) 1363-1367, ISSN 0887-6924 Editore: Nature Publishing Group DOI: 10.1038/leu.2016.384 FBXL13 directs the proteolysis of CEP192 to regulate centrosome homeostasis and cell migration Autori: Ella Fung, Carmen Richter, Hong‐Bin Yang, Isabell Schäffer, Roman Fischer, Benedikt M Kessler, Florian Bassermann, Vincenzo D'Angiolella Pubblicato in: EMBO reports, Issue 19/3, 2018, Page(s) e44799, ISSN 1469-221X Editore: Nature Publishing Group DOI: 10.15252/embr.201744799 Direct modulation of the bone marrow mesenchymal stromal cell compartment by azacitidine enhances healthy hematopoiesis Autori: Catharina Wenk, Anne-Kathrin Garz, Sonja Grath, Christina Huberle, Denis Witham, Marie Weickert, Roberto Malinverni, Julia Niggemeyer, Michèle Kyncl, Judith Hecker, Charlotta Pagel, Christopher B. Mulholland, Catharina Müller-Thomas, Heinrich Leonhardt, Florian Bassermann, Robert A. J. Oostendorp, Klaus H. Metzeler, Marcus Buschbeck, Katharina S. Götze Pubblicato in: Blood Advances, Issue 2/23, 2018, Page(s) 3447-3461, ISSN 2473-9529 Editore: Blood Advances DOI: 10.1182/bloodadvances.2018022053 CHIP and hips: clonal hematopoiesis is common in patients undergoing hip arthroplasty and is associated with autoimmune disease Autori: Judith S. Hecker, Luise Hartmann, Jennifer Rivière, Michèle C. Buck, Mark van der Garde, Maja Rothenberg-Thurley, Luise Fischer, Susann Winter, Bianka Ksienzyk, Frank Ziemann, Maria Solovey, Martina Rauner, Elena Tsourdi, Katja Sockel, Marie Schneider, Anne S. Kubasch, Martin Nolde, Dominikus Hausmann, Alexander C. Paulus, Jörg Lützner, Andreas Roth, Florian Bassermann, Kar Pubblicato in: Blood, Issue 00064971, 2021, ISSN 0006-4971 Editore: American Society of Hematology DOI: 10.1182/blood.2020010163 MLKL promotes cellular differentiation in myeloid leukemia by facilitating the release of G-CSF Autori: Xin Wang, Uris Ros, Deepti Agrawal, Eva C Keller, Julia Slotta-Huspenina, Veronika Dill, Bo Shen, Run Shi, Tobias Herold, Claus Belka, Ritu Mishra, Florian Bassermann, Ana J Garcia-Saez, Philipp J Jost Pubblicato in: Cell Death & Differentiation, Issue 13509047, 2021, ISSN 1350-9047 Editore: Nature Publishing Group DOI: 10.1038/s41418-021-00811-1 Osteoprogenitor SFRP1 prevents exhaustion of hematopoietic stem cells via PP2A-PR72/130-mediated regulation of p300 Autori: Franziska Hettler, Christina Schreck, Sandra Romero Marquez, Thomas Engleitner, Baiba Vilne, Theresa Landspersky, Heike Weidner, Renate Hausinger, Ritu Mishra, Rupert Oellinger, Martina Rauner, Ronald Naumann, Christian Peschel, Florian Bassermann, Roland Rad, Rouzanna Istvanffy, Robert A J Oostendorp Pubblicato in: Haematologica, Issue 03906078, 2022, ISSN 0390-6078 Editore: Ferrata Storti Foundation DOI: 10.3324/haematol.2022.280760 Comprehensive characterization of central BCL-2 family members in aberrant eosinophils and their impact on therapeutic strategies Autori: Timo O Odinius, Lars Buschhorn, Celina Wagner, Richard T Hauch, Veronika Dill, Marta Dechant, Michele C Buck, Khalid Shoumariyeh, Philipp Moog, Juliana Schwaab, Andreas Reiter, Knut Brockow, Katharina Götze, Florian Bassermann, Ulrike Höckendorf, Caterina Branca, Philipp J Jost, Stefanie Jilg Pubblicato in: Journal of Cancer Research and Clinical Oncology, Issue 01715216, 2021, ISSN 0171-5216 Editore: Springer Verlag DOI: 10.1007/s00432-021-03827-9 Implementation of CRISPR/Cas9 Genome Editing to Generate Murine Lung Cancer Models That Depict the Mutational Landscape of Human Disease Autori: Oliver Hartmann, Michaela Reissland, Carina R. Maier, Thomas Fischer, Cristian Prieto-Garcia, Apoorva Baluapuri, Jessica Schwarz, Werner Schmitz, Martin Garrido-Rodriguez, Nikolett Pahor, Clare C. Davies, Florian Bassermann, Amir Orian, Elmar Wolf, Almut Schulze, Marco A. Calzado, Mathias T. Rosenfeldt, Markus E. Diefenbacher Pubblicato in: Frontiers in Cell and Developmental Biology, Issue 9, 2021, ISSN 2296-634X Editore: Front Cell Dev Diol DOI: 10.3389/fcell.2021.641618 Book chapters (1) Cross Talk Networks of Mammalian Target of Rapamycin Signaling With the Ubiquitin Proteasome System and Their Clinical Implications in Multiple Myeloma Autori: Ruth Eichner, Vanesa Fernández-Sáiz, Bianca-Sabrina Targosz, Florian Bassermann Pubblicato in: International Review of Cell and Molecular Biology volume 343, Issue 343, 2019, Page(s) 219-297, ISBN 9780-128167038 Editore: Elsevier DOI: 10.1016/bs.ircmb.2018.06.001 È in corso la ricerca di dati su OpenAIRE... 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