Wiring synaptic circuits with astroglial connexins: mechanisms, dynamics and impact for critical period plasticity

Publications

The intellectual disability protein Oligophrenin1 controls astrocyte morphology and migration: Structural and migratory alterations in astrocytes deficient for OPHN1 via the ROCK pathway

Author(s): Pillet, Laure-Elise; Cresto, Noémie; Saillour, Yoann; Ghézali, Grégory; Bemelmans, Alexis-Pierre; Livet, Jean; Bienvenu, Thierry; Rouach, Nathalie; Billuart, Pierre
Published in: Glia, Issue 3, 2020, ISSN 1098-1136
Publisher: WILEY
DOI: 10.1002/glia.23801

Astrocytes close the mouse critical period for visual plasticity.

Author(s): Jérôme Ribot; Rachel Breton; Rachel Breton; Charles-Félix Calvo; Julien Moulard; Julien Moulard; Pascal Ezan; Jonathan Zapata; Kevin Samama; Matthieu X Moreau; Alexis-Pierre Bemelmans; Valentin Sabatet; Florent Dingli; Damarys Loew; Chantal Milleret; Pierre Billuart; Glenn Dallérac; Nathalie Rouach
Published in: Science, Issue 7, 2021, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.abf5273

Myotonic dystrophy RNA toxicity alters morphology, adhesion and migration of mouse and human astrocytes.

Author(s): Diana M. Dincã; Louison Lallemant; Anchel González-Barriga; Noémie Cresto; Sandra O. Braz; Géraldine Sicot; Laure-Elise Pillet; Hélène Polvèche; Paul Magneron; Aline Huguet-Lachon; Hélène Benyamine; Cuauhtli N. Azotla-Vilchis; Luis E. Agonizantes-Juárez; Julie Tahraoui-Bories; Cécile Martinat; Oscar Hernández-Hernández; Didier Auboeuf; Nathalie Rouach; Cyril F. Bourgeois; Geneviève G
Published in: Nature Communications, Issue 5, 2022, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-022-31594-9

Astroglial Cx30 differentially impacts synaptic activity from hippocampal principal cells and interneurons

Author(s): Eléonore Hardy; Martine Cohen-Salmon; Nathalie Rouach; Armelle Rancillac
Published in: GLIA, Issue 11, 2021, ISSN 0894-1491
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/glia.24017

Les astrocytes, gardiens de la plasticité des périodes critiques

Author(s): Jérôme Ribot; Rachel Breton; Glenn Dallérac; Nathalie Rouach
Published in: Médecine Sciences, Issue 5, 2022, ISSN 0767-0974
Publisher: Editions E D K
DOI: 10.1051/medsci/2022014

Physiological synaptic activity and recognition memory require astroglial glutamine

Author(s): Giselle Cheung, Danijela Bataveljic, Josien Visser, Naresh Kumar, Julien Moulard, Glenn Dallérac, Daria Mozheiko, Astrid Rollenhagen, Pascal Ezan, Cédric Mongin, Oana Chever, Alexis-Pierre Bemelmans, Joachim Lübke, Isabelle Leray, Nathalie Rouach
Published in: NATURE COMMUNICATIONS, 2022, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-022-28331-7

Hippocampal Excitatory Synaptic Transmission and Plasticity Are Differentially Altered during Postnatal Development by Loss of the X-Linked Intellectual Disability Protein Oligophrenin-1

Author(s): Noemie Cresto; Nicolas Lebrun; Florent Dumont; Franck Letourneur; Pierre Billuart; Nathalie Rouach
Published in: "Cells, 2022, 11 (9), pp.1545. ⟨10.3390/cells11091545⟩", Issue 1, 2022, ISSN 2073-4409
Publisher: MDPI
DOI: 10.3390/cells11091545

The many ways astroglial connexins regulate neurotransmission and behavior.

Author(s): David Mazaud; Anna Capano; Anna Capano; Nathalie Rouach
Published in: GLIA, Issue 5, 2021, ISSN 0894-1491
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/glia.24040

Dynamics of Ion Fluxes between Neurons, Astrocytes and the Extracellular Space during Neurotransmission

Author(s): N. Rouach, K. Dao Duc, J. Sibille, D. Holcman
Published in: Opera Medica et Physiologica, Issue Vol. 4 (1), 2018, Page(s) 1-18, ISSN 2500-2287
Publisher: Opera Medica et Physiologica
DOI: 10.20388/omp2018.001.0053

Connexin 30 controls astroglial polarization during postnatal brain development

Author(s): Grégory Ghézali, Charles-Félix Calvo, Laure-Elise Pillet, Flora Llense, Pascal Ezan, Ulrike Pannasch, Alexis-Pierre Bemelmans, Sandrine Etienne Manneville, Nathalie Rouach
Published in: Development, Issue 145/4, 2018, Page(s) dev155275, ISSN 0950-1991
Publisher: The Company of Biologists Ltd.
DOI: 10.1242/dev.155275

Human astrocytes: structure and functions in the healthy brain

Author(s): Flora Vasile, Elena Dossi, Nathalie Rouach
Published in: Brain Structure and Function, Issue 222/5, 2017, Page(s) 2017-2029, ISSN 1863-2653
Publisher: Springer Verlag
DOI: 10.1007/s00429-017-1383-5

Human astrocytes in the diseased brain

Author(s): Elena Dossi, Flora Vasile, Nathalie Rouach
Published in: Brain Research Bulletin, Issue 136, 2018, Page(s) 139-156, ISSN 0361-9230
Publisher: Elsevier BV
DOI: 10.1016/j.brainresbull.2017.02.001

Connexin 30 is expressed in a subtype of mouse brain pericytes

Author(s): Noémie Mazaré, Alice Gilbert, Anne-Cécile Boulay, Nathalie Rouach, Martine Cohen-Salmon
Published in: Brain Structure and Function, Issue 223/2, 2018, Page(s) 1017-1024, ISSN 1863-2653
Publisher: Springer Verlag
DOI: 10.1007/s00429-017-1562-4

Gamma-aminobutyric acidergic transmission underlies interictal epileptogenicity in pediatric focal cortical dysplasia

Author(s): Thomas Blauwblomme, Elena Dossi, Christophe Pellegrino, Emmanuelle Goubert, Beatriz Gal Iglesias, Christian Sainte-Rose, Nathalie Rouach, Rima Nabbout, Gilles Huberfeld
Published in: Annals of Neurology, Issue 85/2, 2019, Page(s) 204-217, ISSN 0364-5134
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/ana.25403

Correlative STED and Atomic Force Microscopy on Live Astrocytes Reveals Plasticity of Cytoskeletal Structure and Membrane Physical Properties during Polarized Migration

Author(s): Nathan Curry, Grégory Ghézali, Gabriele S. Kaminski Schierle, Nathalie Rouach, Clemens F. Kaminski
Published in: Frontiers in Cellular Neuroscience, Issue 11, 2017, ISSN 1662-5102
Publisher: Frontiers Research Foundation
DOI: 10.3389/fncel.2017.00104

Versatile control of synaptic circuits by astrocytes: where, when and how?

Author(s): Glenn Dallérac, Jonathan Zapata, Nathalie Rouach
Published in: Nature Reviews Neuroscience, Issue 19/12, 2018, Page(s) 729-743, ISSN 1471-003X
Publisher: Nature Publishing Group
DOI: 10.1038/s41583-018-0080-6

Pannexin-1 channels contribute to seizure generation in human epileptic brain tissue and in a mouse model of epilepsy

Author(s): Elena Dossi, Thomas Blauwblomme, Julien Moulard, Oana Chever, Flora Vasile, Eleonore Guinard, Marc Le Bert, Isabelle Couillin, Johan Pallud, Laurent Capelle, Gilles Huberfeld, Nathalie Rouach
Published in: Science Translational Medicine, Issue 10/443, 2018, Page(s) eaar3796, ISSN 1946-6234
Publisher: American Association for the Advancement of Science
DOI: 10.1126/scitranslmed.aar3796

Do Astrocytes Play a Role in Intellectual Disabilities?

Author(s): Noémie Cresto, Laure-Elise Pillet, Pierre Billuart, Nathalie Rouach
Published in: Trends in Neurosciences, Issue 42/8, 2019, Page(s) 518-527, ISSN 0166-2236
Publisher: Elsevier BV
DOI: 10.1016/j.tins.2019.05.011

Neuronal Activity Drives Astroglial Connexin 30 in Perisynaptic Processes and Shapes Its Functions

Author(s): Grégory Ghézali, Flora Vasile, Nathan Curry, Marcus Fantham, Giselle Cheung, Pascal Ezan, Martine Cohen-Salmon, Clemens Kaminski, Nathalie Rouach
Published in: Cerebral Cortex, 2019, ISSN 1047-3211
Publisher: Oxford University Press
DOI: 10.1093/cercor/bhz123

Fast calcium transients in dendritic spines driven by extreme statistics

Author(s): Kanishka Basnayake, David Mazaud, Alexis Bemelmans, Nathalie Rouach, Eduard Korkotian, David Holcman
Published in: PLOS Biology, Issue 17/6, 2019, Page(s) e2006202, ISSN 1545-7885
Publisher: PLOS
DOI: 10.1371/journal.pbio.2006202

Astroglial Cx30 sustains neuronal population bursts independently of gap‐junction mediated biochemical coupling

Author(s): Ulrike Pannasch, Elena Dossi, Pascal Ezan, Nathalie Rouach
Published in: Glia, Issue 67/6, 2019, Page(s) 1104-1112, ISSN 0894-1491
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/glia.23591

Astrocytes mediate the effect of oxytocin in the central amygdala on neuronal activity and affective states in rodents

Author(s): Jérôme Wahis, Angel Baudon, Ferdinand Althammer, Damien Kerspern, Stéphanie Goyon, Daisuke Hagiwara, Arthur Lefevre, Lara Barteczko, Benjamin Boury-Jamot, Benjamin Bellanger, Marios Abatis, Miriam Da Silva Gouveia, Diego Benusiglio, Marina Eliava, Andrei Rozov, Ivan Weinsanto, Hanna Sophie Knobloch-Bollmann, Matthew K Kirchner, Ranjan K Roy, Hong Wang, Marie Pertin, Perrine Inquimbert, Claudia
Published in: Nature Neuroscience, 2021, ISSN 1546-1726
Publisher: Nature Research
DOI: 10.1038/s41593-021-00800-0

Local translation in perisynaptic astrocytic processes is specific and regulated by fear conditioning

Author(s): Noémie Mazaré; Noémie Mazaré; Marc Oudart; Julien Moulard; Giselle Cheung; Romain Tortuyaux; Philippe Mailly; David Mazaud; Alexis-Pierre Bemelmans; Anne-Cécile Boulay; Corinne Blugeon; Laurent Jourdren; Stéphane Le Crom; Stéphane Le Crom; Nathalie Rouach; Martine Cohen-Salmon
Published in: Cell Reports, Issue 15, 2020, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2020.108076

Nanoscale molecular architecture controls calcium diffusion and ER replenishment in dendritic spines

Author(s): Kanishka Basnayake, David Mazaud, Lilia Kushnireva, Alexis Bemelmans, Nathalie Rouach, Eduard Korkotian, David Holcman
Published in: SCIENCE ADVANCES, 2021, ISSN 2375-2548
Publisher: American Association for the Advancement of Science
DOI: 10.1126/sciadv.abh1376