Mechanism of Enzyme Rhodopsin Activation

Project Information

MERA

Grant agreement ID: 693742

DOI 10.3030/693742

Project closed

EC signature date 26 August 2016

Start date 1 October 2016

End date 30 September 2021

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 2 398 750,00

EU contribution € 2 398 750,00

Coordinated by

HUMBOLDT-UNIVERSITAET ZU BERLIN
Germany

Publications

Peer reviewed articles (6)

Optogenetic tools for manipulation of cyclic nucleotides, functionally coupled to CNG-channels

Author(s): Henß T., Nagpal J., Gao S., Scheib U., Pieragnolo, A., Hirschhäuser A., Schneider-Warme, F., Hegemann P., Nagel, G. and Gottschalk A.
Published in: British Journal of Pharmacology, Issue 179, 2021, Page(s) 2519–2537, ISSN 0007-1188
Publisher: Wiley-Blackwell
DOI: 10.1111/bph.15445

Rhodopsin for near-infrared light sensing

Author(s): Broser M., Spreen, A., Konold, P.E., Peter E., Adam S., Borin V., Schapiro I., Seifert R., Kennis J.T.M., Bernal Sierra Y.A., and Hegemann P.
Published in: Nature Comm, Issue 11, 2020, Page(s) 5682, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-020-19375-8

The inner mechanics of Rhodopsin Guanylyl Cyclase during cGMP-formation revealed by real-time FTIR spectroscopy

Author(s): Fischer P., Mukherjee S., Peter E., Broser M., Bartl F., Hegemann P.
Published in: eLife, Issue 10, 2021, Page(s) e71384, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.71384

Absorption and Emission Spectroscopic Investigation of Thermal Dynamics and Photo-Dynamics of the Rhodopsin Domain of the Rhodopsin-Guanylyl Cyclase from the Nematophagous Fungus Catenaria anguillulae

Author(s): Alfons Penzkofer, Ulrike Scheib, Katja Stehfest, Peter Hegemann
Published in: International Journal of Molecular Sciences, Issue 18/10, 2017, Page(s) 2099, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms18102099

Rhodopsin-cyclases for photocontrol of cGMP/cAMP and 2.3 Å structure of the adenylyl cyclase domain

Author(s): Ulrike Scheib, Matthias Broser, Oana M. Constantin, Shang Yang, Shiqiang Gao, Shatanik Mukherjee, Katja Stehfest, Georg Nagel, Christine E. Gee, Peter Hegemann
Published in: Nature Communications, Issue 9/1, 2018, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-018-04428-w

Enzymerhodopsins: novel photoregulated catalysts for optogenetics

Author(s): Shatanik Mukherjee, Peter Hegemann, Matthias Broser
Published in: Current Opinion in Structural Biology, Issue 57, 2019, Page(s) 118-126, ISSN 0959-440X
Publisher: Elsevier BV
DOI: 10.1016/j.sbi.2019.02.003

Thesis and dissertations (2)

Investigation on rhodopsin guanylyl cyclase from Catenaria emersonii with a new combined FTIR and UV-Vis spectrometer

Author(s): Fischer, P.
Published in: 2021
Publisher: Humboldt-Universität zu Berlin

Biochemische und biophysikalische Charakterisierung von Rhodopsin-Guanylylzyklasen.

Author(s): Ulrike Scheib
Published in: 2019
Publisher: Scheib, U.