Repeat polymorphisms as genetic modifiers of brain function in healthy subjects and Huntington disease mutation carriers

Informazioni relative al progetto

BRAIN REPEATS

ID dell’accordo di sovvenzione: 701130

DOI 10.3030/701130

Progetto chiuso

Data della firma CE 7 Marzo 2016

Data di avvio 1 Ottobre 2016

Data di completamento 30 Settembre 2017

Finanziato da

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Costo totale € 97 727,40

Contributo UE € 97 727,40

Coordinato da

UNIVERSITY COLLEGE LONDON
United Kingdom

Pubblicazioni

Peer reviewed articles (5)

Co-expression patterns between ATN1 and ATXN2 coincide with brain regions affected in Huntington's disease

Autori: Arlin Keo, N. Ahmad Aziz, Oleh Dzyubachyk, Jeroen van der Grond, Willeke van Roon-Mom, Boudewijn Lelieveldt, Marcel Reinders, Ahmed Mahfouz
Pubblicato in: Front. Mol. Neurosci., 2017, ISSN 1662-5099
Editore: Frontiers Research Foundation
DOI: 10.3389/fnmol.2017.00399

The Missing Link in Polyglutamine Diseases

Autori: N. Ahmad Aziz, Bettina Balint
Pubblicato in: Movement Disorders Clinical Practice, 2017, ISSN 2330-1619
Editore: Wiley
DOI: 10.1002/mdc3.12558

Body weight is a robust predictor of clinical progression in Huntington disease

Autori: Jorien M. M. van der Burg, Sarah L. Gardiner, Albert C. Ludolph, G. Bernhard Landwehrmeyer, Raymund A. C. Roos, N. Ahmad Aziz
Pubblicato in: Annals of Neurology, Numero 82/3, 2017, Pagina/e 479-483, ISSN 0364-5134
Editore: John Wiley & Sons Inc.
DOI: 10.1002/ana.25007

Age of onset in Huntington’s disease is influenced by CAG repeat variations in other polyglutamine disease-associated genes

Autori: Geerte Stuitje, Martine J. van Belzen, Sarah L. Gardiner, Willeke M. C. van Roon-Mom, Merel W. Boogaard, Sarah J. Tabrizi, Raymund A. C. Roos, N. A. Aziz
Pubblicato in: Brain, Numero 140/7, 2017, Pagina/e e42-e42, ISSN 0006-8950
Editore: Oxford University Press
DOI: 10.1093/brain/awx122

Large normal-range TBP and ATXN7 CAG repeat lengths are associated with increased lifetime risk of depression

Autori: S L Gardiner, M J van Belzen, M W Boogaard, W M C van Roon-Mom, M P Rozing, A M van Hemert, J H Smit, A T F Beekman, G van Grootheest, R A Schoevers, R C Oude Voshaar, H C Comijs, B W J H Penninx, R C van der Mast, R A C Roos, N A Aziz
Pubblicato in: Translational Psychiatry, Numero 7/6, 2017, Pagina/e e1143, ISSN 2158-3188
Editore: Nature Publishing Group
DOI: 10.1038/tp.2017.116