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EaRly Nutrition programming- long term Efficacy and Safety Trials and integrated epidemiological, genetic, animal, consumer and economic research. [EARNEST]

Obiettivo

What is known: post-natal nutritional programming of adult health is demonstrated by 1 Experi- mental animal studies 2 Historical; prospective human observational studies linking size at birth & infancy with adult disease 3 Experimental studies in selected groups of humans with limited follow-up. What is not known: The importance of early nutritional programming. to contemporary EU populations, precise nutritional exposures, timing; mechanisms, nor effectiveness of interven- tions to reverse adverse effects. EARNEST will establish: T9 a multi-disciplinary team of leading international scientists from major research centres across Europe working on critical aspects of nutritional programming, co-ordinated by professional management, with strong horizontal, verti- cal; sectoral integration T1 nutritional programming of adult disease risk by measuring adult disease markers in well-conducted randomised controlled trials of specific nutrition interventions in preg- nancy; infancy T2 quantitative importance of nut. prgr. in contemporary adult EU populations by examining later outcome in large well-characterised population-based prospective studies T3 mechanisms of nut. prgr. using functional genomics in animal, cellular and molecular studies T4 consumer attitudes to nutritional programming. T5 economic impact of nut. prgr. T6 demonstration projects to test new technologies with economic potential T7 professional approach to outreach; communication T8 multi-disciplinary training EARNEST outcomes: Best data from human trials; prospective studies, state of the art determination of mechanisms, critical time periods, key genes implicated in programming, evidence to guide improvements in infant formula; to formulate poli- cies on their composition; testing, interventions proven to prevent; reverse nutritional programming, potential to develop new products with industry, information on socio-economic costs.

Campo scientifico

Parole chiave

Programma(i)

Argomento(i)

Invito a presentare proposte

FP6-2003-FOOD-2-A
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Meccanismo di finanziamento

IP - Integrated Project

Coordinatore

LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN
Contributo UE
Nessun dato
Indirizzo
Geschwister-Scholl-Platz 1
MUNICH
Germania

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Ultimo aggiornamento: 26 Marzo 2013

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Permalink: https://cordis.europa.eu/project/id/7036/it

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