Obiettivo The lost of the eye’s capability to accommodate near and far objects (known as presbyopia) affects 100% of the population >45, i.e. 200 million in Europe and 1.200 million worldwide. Multifocal corrections, in the form of contact lenses (CLs), intraocular lenses (IOLs) or corneal surgery are increasingly used solutions to restore vision functionality in presbyopes. These corrections are based on the simultaneous vision principle, where a focused image and a defocused image are simultaneously projected on the retina. How a simultaneous image looks like is difficult to imagine. To date, prescription of a multifocal correction is based on the surgeon’s experience and conversations with the patient. In CLs solutions, the process requires multiple trials and errors with different lenses. In cataract surgery, patient’s unsatisfaction often results in IOL explantation.The PRESBYOPIA ERC-Advanced Grant investigates basic mechanisms of the crystalline lens accommodation, to propose nature-inspired designs to correct presbyopia, multifocal lenses in particular. We have developed Adaptive-Optics visual simulators to simulate corrections before they are manufactured or implanted in a patient. In particular, we have developed novel simultaneous vision simulators (an optical bench instrument, and a see-through portable clinical prototype) that allow patients to see the world under programmed multifocal IOLs. We have demonstrated their capabilities to mimic commercial multifocal designs, visual performance with different design parameters and neural adaptation to simultaneous vision. The SimVisSim ERC-Proof of Concept will evaluate the marketability of the SimVis Technology, generating new IP, develop a technology transfer strategy, and a product commercialization plan, with the ultimate goal of deploying a clinical device in the market. This should bring eye surgery and presbyopia treatments into new paradigms for lens selection and customization. Campo scientifico medical and health sciencesclinical medicinesurgerymedical and health sciencesclinical medicineophthalmology Programma(i) H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC) Main Programme Argomento(i) ERC-PoC-2015 - ERC Proof of Concept Grant Invito a presentare proposte ERC-2015-PoC Vedi altri progetti per questo bando Meccanismo di finanziamento ERC-POC - Proof of Concept Grant Istituzione ospitante AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS Contribution nette de l'UE € 150 000,00 Indirizzo CALLE SERRANO 117 28006 Madrid Spagna Mostra sulla mappa Regione Comunidad de Madrid Comunidad de Madrid Madrid Tipo di attività Research Organisations Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Partecipazione a programmi di R&I dell'UE Opens in new window Rete di collaborazione HORIZON Opens in new window Costo totale € 150 000,00 Beneficiari (1) Classifica in ordine alfabetico Classifica per Contributo netto dell'UE Espandi tutto Riduci tutto AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS Spagna Contribution nette de l'UE € 150 000,00 Indirizzo CALLE SERRANO 117 28006 Madrid Mostra sulla mappa Regione Comunidad de Madrid Comunidad de Madrid Madrid Tipo di attività Research Organisations Collegamenti Contatta l’organizzazione Opens in new window Sito web Opens in new window Partecipazione a programmi di R&I dell'UE Opens in new window Rete di collaborazione HORIZON Opens in new window Costo totale € 150 000,00