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The evolutionary ecology of bacterial immune mechanisms

Pubblicazioni

Phage gene expression and host responses lead to infection-dependent costs of CRISPR immunity

Autori: Sean Meaden, Loris Capria, Ellinor Alseth, Sylvain Gandon, Ambarish Biswas, Luca Lenzi, Stineke van Houte, Edze R. Westra
Pubblicato in: The ISME Journal, Issue 15/2, 2021, Page(s) 534-544, ISSN 1751-7362
Editore: Nature Publishing Group
DOI: 10.1038/s41396-020-00794-w

Coevolution between bacterial CRISPR-Cas systems and their bacteriophages

Autori: Bridget N.J. Watson, Jurre A. Steens, Raymond H.J. Staals, Edze R. Westra, Stineke van Houte
Pubblicato in: Cell Host & Microbe, Issue 29/5, 2021, Page(s) 715-725, ISSN 1931-3128
Editore: Cell Press
DOI: 10.1016/j.chom.2021.03.018

Anti-CRISPR Phages Cooperate to Overcome CRISPR-Cas Immunity

Autori: Mariann Landsberger, Sylvain Gandon, Sean Meaden, Clare Rollie, Anne Chevallereau, Hélène Chabas, Angus Buckling, Edze R. Westra, Stineke van Houte
Pubblicato in: Cell, Issue 174/4, 2018, Page(s) 908-916.e12, ISSN 0092-8674
Editore: Cell Press
DOI: 10.1016/j.cell.2018.05.058

The effect of bacterial mutation rate on the evolution of CRISPR-Cas adaptive immunity

Autori: Anne Chevallereau, Sean Meaden, Stineke van Houte, Edze R. Westra, Clare Rollie
Pubblicato in: Philosophical Transactions of the Royal Society B: Biological Sciences, Issue 374/1772, 2019, Page(s) 20180094, ISSN 0962-8436
Editore: Royal Society of London
DOI: 10.1098/rstb.2018.0094

Variability in the durability of CRISPR-Cas immunity

Autori: Hélène Chabas, Antoine Nicot, Sean Meaden, Edze R. Westra, Denise M. Tremblay, Léa Pradier, Sébastien Lion, Sylvain Moineau, Sylvain Gandon
Pubblicato in: Philosophical Transactions of the Royal Society B: Biological Sciences, Issue 374/1772, 2019, Page(s) 20180097, ISSN 0962-8436
Editore: Royal Society of London
DOI: 10.1098/rstb.2018.0097

Evolutionary emergence of infectious diseases in heterogeneous host populations

Autori: Hélène Chabas, Sébastien Lion, Antoine Nicot, Sean Meaden, Stineke van Houte, Sylvain Moineau, Lindi M. Wahl, Edze R. Westra, Sylvain Gandon
Pubblicato in: PLOS Biology, Issue 16/9, 2018, Page(s) e2006738, ISSN 1545-7885
Editore: PLoS
DOI: 10.1371/journal.pbio.2006738

CRISPR-Cas immunity leads to a coevolutionary arms race between Streptococcus thermophilus and lytic phage

Autori: Jack Common, Daniel Morley, Edze R. Westra, Stineke van Houte
Pubblicato in: Philosophical Transactions of the Royal Society B: Biological Sciences, Issue 374/1772, 2019, Page(s) 20180098, ISSN 0962-8436
Editore: Royal Society of London
DOI: 10.1098/rstb.2018.0098

CRISPR-Cas antimicrobials: Challenges and future prospects

Autori: Elizabeth Pursey, David Sünderhauf, William H. Gaze, Edze R. Westra, Stineke van Houte
Pubblicato in: PLOS Pathogens, Issue 14/6, 2018, Page(s) e1006990, ISSN 1553-7374
Editore: PLoS
DOI: 10.1371/journal.ppat.1006990

CRISPR evolution and bacteriophage persistence in the context of population bottlenecks

Autori: Jack Common, Edze R. Westra
Pubblicato in: RNA Biology, Issue 16/4, 2018, Page(s) 588-594, ISSN 1547-6286
Editore: Landes Bioscience
DOI: 10.1080/15476286.2019.1578608

Recombination between phages and CRISPR−cas loci facilitates horizontal gene transfer in staphylococci

Autori: Andrew Varble, Sean Meaden, Rodolphe Barrangou, Edze R. Westra, Luciano A. Marraffini
Pubblicato in: Nature Microbiology, Issue 4/6, 2019, Page(s) 956-963, ISSN 2058-5276
Editore: Nature press
DOI: 10.1038/s41564-019-0400-2

Addiction systems antagonize bacterial adaptive immunity

Autori: Lisa van Sluijs, Stineke van Houte, John van der Oost, Stan JJ Brouns, Angus Buckling, Edze R Westra
Pubblicato in: FEMS Microbiology Letters, Issue 366/5, 2019, ISSN 1574-6968
Editore: Oxford academic
DOI: 10.1093/femsle/fnz047

Exploitation of the Cooperative Behaviors of Anti-CRISPR Phages

Autori: Anne Chevallereau, Sean Meaden, Olivier Fradet, Mariann Landsberger, Alice Maestri, Ambarish Biswas, Sylvain Gandon, Stineke van Houte, Edze R. Westra
Pubblicato in: Cell Host & Microbe, 2019, ISSN 1931-3128
Editore: Cell Press
DOI: 10.1016/j.chom.2019.12.004

The effect of phage genetic diversity on bacterial resistance evolution

Autori: Jenny M. Broniewski, Sean Meaden, Steve Paterson, Angus Buckling, Edze R. Westra
Pubblicato in: The ISME Journal, 2020, ISSN 1751-7362
Editore: Nature Publishing Group
DOI: 10.1038/s41396-019-0577-7

Targeting of temperate phages drives loss of type I CRISPR–Cas systems

Autori: Clare Rollie, Anne Chevallereau, Bridget N. J. Watson, Te-yuan Chyou, Olivier Fradet, Isobel McLeod, Peter C. Fineran, Chris M. Brown, Sylvain Gandon, Edze R. Westra
Pubblicato in: Nature, 2020, ISSN 0028-0836
Editore: Nature Publishing Group
DOI: 10.1038/s41586-020-1936-2

Bacterial biodiversity drives the evolution of CRISPR-based phage resistance

Autori: Ellinor O. Alseth, Elizabeth Pursey, Adela M. Luján, Isobel McLeod, Clare Rollie, Edze R. Westra
Pubblicato in: Nature, Issue 574/7779, 2019, Page(s) 549-552, ISSN 0028-0836
Editore: Nature Publishing Group
DOI: 10.1038/s41586-019-1662-9

It is unclear how important CRISPR-Cas systems are for protecting natural populations of bacteria against infections by mobile genetic elements

Autori: Edze R. Westra, Bruce R. Levin
Pubblicato in: Proceedings of the National Academy of Sciences, Issue 117/45, 2020, Page(s) 27777-27785, ISSN 0027-8424
Editore: National Academy of Sciences
DOI: 10.1073/pnas.1915966117

Evolutionary Ecology and Interplay of Prokaryotic Innate and Adaptive Immune Systems

Autori: Tatiana Dimitriu, Mark D. Szczelkun, Edze R. Westra
Pubblicato in: Current Biology, Issue 30/19, 2020, Page(s) R1189-R1202, ISSN 0960-9822
Editore: Cell Press
DOI: 10.1016/j.cub.2020.08.028

Avoidance of Self during CRISPR Immunization

Autori: Jake L. Weissman, Arlin Stoltzfus, Edze R. Westra, Philip L.F. Johnson
Pubblicato in: Trends in Microbiology, Issue 28/7, 2020, Page(s) 543-553, ISSN 0966-842X
Editore: Elsevier BV
DOI: 10.1016/j.tim.2020.02.005

The effect of Quorum sensing inhibitors on the evolution of CRISPR-based phage immunity in Pseudomonas aeruginosa

Autori: Jenny M. Broniewski, Matthew A. W. Chisnall, Nina Molin Høyland-Kroghsbo, Angus Buckling, Edze R. Westra
Pubblicato in: The ISME Journal, 2021, ISSN 1751-7362
Editore: Nature Publishing Group
DOI: 10.1038/s41396-021-00946-6

Diversity in CRISPR‐based immunity protects susceptible genotypes by restricting phage spread and evolution

Autori: Jack Common, David Walker‐Sünderhauf, Stineke Houte, Edze R. Westra
Pubblicato in: Journal of Evolutionary Biology, Issue 33/8, 2020, Page(s) 1097-1108, ISSN 1010-061X
Editore: Blackwell Publishing Inc.
DOI: 10.1111/jeb.13638

The ecology and evolution of microbial CRISPR-Cas adaptive immune systems

Autori: Edze R. Westra, Stineke van Houte, Sylvain Gandon, Rachel Whitaker
Pubblicato in: Philosophical Transactions of the Royal Society B: Biological Sciences, Issue 374/1772, 2019, Page(s) 20190101, ISSN 0962-8436
Editore: Royal Society of London
DOI: 10.1098/rstb.2019.0101

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