Glioblastoma Subtype Avatar models for Target Discovery and Biology

Informazioni relative al progetto

iGBMavatars

ID dell’accordo di sovvenzione: 714922

DOI 10.3030/714922

Progetto chiuso

Data della firma CE 1 Dicembre 2016

Data di avvio 1 Luglio 2017

Data di completamento 30 Giugno 2023

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale € 1 500 000,00

Contributo UE € 1 500 000,00

Coordinato da

MAX DELBRUECK CENTRUM FUER MOLEKULARE MEDIZIN IN DER HELMHOLTZ-GEMEINSCHAFT (MDC)
Germany

Pubblicazioni

Peer reviewed articles (8)

USP15 Deubiquitinase Safeguards Hematopoiesis and Genome Integrity in Hematopoietic Stem Cells and Leukemia Cells

Autori: Paul van den Berk, Cesare Lancini, Carlos Company, Michela Serresi, Maria Pilar Sanchez-Bailon, Danielle Hulsman, Colin Pritchard, Ji-Ying Song, Matthias Jürgen Schmitt, Ellen Tanger, Oliver Popp, Philipp Mertins, Ivo J Huijbers, Heinz Jacobs, Maarten van Lohuizen, Gaetano Gargiulo, Elisabetta Citterio
Pubblicato in: Cell Reports, 2020, ISSN 2639-1856
Editore: Elsevier
DOI: 10.1016/j.celrep.2020.108533

Molecular identity of proprioceptor subtypes innervating different muscle groups in mice

Autori: Stephan Dietrich, Carlos Company, Kun Song, Elijah David Lowenstein, Levin Riedel, Carmen Birchmeier, Gaetano Gargiulo, Niccolò Zampieri
Pubblicato in: Nature Communications, 2023, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-022-34589-8

NF1 regulates mesenchymal glioblastoma plasticity and aggressiveness through the AP-1 transcription factor FOSL1.

Autori: Carolina Marques; Thomas Unterkircher; Paula Kroon; Barbara Oldrini; Annalisa Izzo; Yuliia Dramaretska; Roberto Ferrarese; Eva Kling; Oliver Schnell; Sven Nelander; Erwin F. Wagner; Latifa Bakiri; Gaetano Gargiulo; Maria Stella Carro; Massimo Squatrito
Pubblicato in: eLife, Numero 2, 2021, ISSN 2050-084X
Editore: eLife Sciences Publications
DOI: 10.7554/elife.64846

Phenotypic Mapping of Pathologic Cross-Talk between Glioblastoma and Innate Immune Cells by Synthetic Genetic Tracing

Autori: Matthias Jürgen Schmitt; Carlos Company; Yuliia Dramaretska; Iros Barozzi; Andreas Göhrig; Sonia Kertalli; Melanie Großmann; Heike Naumann; Maria Pilar Sanchez-Bailon; Danielle Hulsman; Rainer Glass; Massimo Squatrito; Michela Serresi; Gaetano Gargiulo
Pubblicato in: Cancer Discov, 2021, ISSN 2159-8274
Editore: American Association for Cancer Research Inc.
DOI: 10.1158/2159-8290.cd-20-0219

Pharmacological modulators of epithelial immunity uncovered by synthetic genetic tracing of SARS-CoV-2 infection responses

Autori: Ben Jiang, Matthias Jürgen Schmitt, Ulfert Rand, Carlos Company, Yuliia Dramaretska, Melanie Grossmann, Michela Serresi, Luka Čičin-Šain, Gaetano Gargiulo
Pubblicato in: Science Advances, 2023, ISSN 2375-2548
Editore: AAAS
DOI: 10.1126/sciadv.adf4975

Next-Generation in vivo Modeling of Human Cancers

Autori: Gaetano Gargiulo
Pubblicato in: Frontiers in Oncology, Numero 8, 2018, ISSN 2234-943X
Editore: Frontiers Media S. A.
DOI: 10.3389/fonc.2018.00429

Functional antagonism of chromatin modulators regulates epithelial-mesenchymal transition

Autori: Michela Serresi; Sonia Kertalli; Lifei Li; Matthias Jürgen Schmitt; Yuliia Dramaretska; Jikke Wierikx; Danielle Hulsman; Gaetano Gargiulo
Pubblicato in: Science Advances, Numero 1, 2021, ISSN 2375-2548
Editore: American Association for the Advancement of Science
DOI: 10.1126/sciadv.abd7974

Cannabidiol converts NF-κB into a tumor suppressor in glioblastoma with defined antioxidative properties

Autori: Marie N M Volmar, Jiying Cheng, Haitham Alenezi, Sven Richter, Alisha Haug, Zonera Hassan, Maria Goldberg, Yuping Li, Mengzhuo Hou, Christel Herold-Mende, Cecile L Maire, Katrin Lamszus, Charlotte Flüh, Janka Held-Feindt, Gaetano Gargiulo, Geoffrey J Topping, Franz Schilling, Dieter Saur, Günter Schneider, Michael Synowitz, Joel A Schick, Roland E Kälin, Rainer Glass
Pubblicato in: Neuro-Oncology, 2021, ISSN 1522-8517
Editore: Duke University Press
DOI: 10.1093/neuonc/noab095